Jun 15, 2024
Deep model predictive control of gene expression in thousands of single cells
Posted by Dan Breeden in categories: biotech/medical, chemistry, robotics/AI
Gene expression is inherently dynamic, due to complex regulation and stochastic biochemical events. Here the authors train a deep neural network to predict and dynamically control gene expression in thousands of individual bacteria in real-time which they then apply to control antibiotic resistance and study single-cell survival dynamics.