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Researchers at the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) have invented an oral formulation of arsenic trioxide (Oral-ATO; ARSENOL) for the treatment of acute promyelocytic leukemia (APL), a blood cancer that once had a high fatality rate.

The invention and use of oral-ATO is of historic importance for medicine in Hong Kong. It is the first-ever prescription medication wholly invented and manufactured in Hong Kong, and also the first to obtain U.S., European and Japanese patents.

After more than two decades of dedicated work, the HKU research team successfully translated this Hong Kong invention into by incorporating oral-ATO into the treatment plan of APL patients. Extensive clinical studies of oral-ATO have demonstrated its high efficacy and safety in curing APL patients, with an overall survival (OS) rate exceeding 97%, along with a significant reduction in side-effects and treatment burden.

Their new stabilization method overcomes disruptions, keeping the network running smoothly and securely.

Quantum Breakthrough: First Entangled Signal Over Commercial Network

Researchers from the Department of Energy’s Oak Ridge National Laboratory (ORNL), EPB of Chattanooga, and the University of Tennessee at Chattanooga have successfully transmitted an entangled quantum signal over a commercial fiber-optic network. This achievement marks the first time multiple wavelength channels and automatic polarization stabilization have been used together — without any network downtime.

Scientists have developed a revolutionary catalyst that not only converts CO2 into valuable products but actually increases in activity over time.

Made from tin microparticles on a nanotextured carbon structure, this innovative electrocatalyst efficiently produces formate—a key compound for various industries. Unlike conventional catalysts that degrade, this one self-optimizes by breaking down into smaller tin nanoparticles, dramatically improving performance.

Breakthrough Catalyst for CO2 Conversion.

Researchers at the Biomimetics-Innovation-Center, Hochschule Bremen—City University of Applied Sciences, have made pioneering discoveries about how mechanical stress shapes the ultrastructure of starfish skeletons. Published in Acta Biomaterialia, their study delivers the first in-depth analysis of how starfish skeletons respond to varying stress conditions, revealing new insights into the evolutionary mechanisms that drive skeletal adaptation.

While starfish are widely recognized—especially thanks to pop-culture icons like Patrick Star in SpongeBob SquarePants—their remarkable internal structure often goes unnoticed. Sharing an evolutionary lineage with vertebrates, starfish serve as powerful models for studying the development of endoskeletons.

Their skeletons consist of thousands of small, bone-like elements called ossicles, which feature a complex, porous structure strikingly similar to human and other vertebrate bones. According to lead author Raman and colleagues, these ossicles exhibit microstructural adaptations that mirror the they experience, demonstrating a universal principle of stress adaptation.

This allows them to see how bacteria activate different genes in response to their environment, offering insights into microbial behavior, antibiotic resistance, and infection strategies.

How Bacteria Organize Their Activities

How do bacteria — whether beneficial ones in our bodies or harmful disease-causing strains — coordinate their activities? A recent study has provided new insights by combining advanced genomic-scale microscopy with an innovative technique to track which genes bacteria activate in different conditions and environments. Published recently in the journal Science, this breakthrough is set to advance bacterial research significantly.

Enter laser-plasma accelerators (LPAs). LPAs use high-intensity lasers to strike a target, generating charged particle beams that reach comparable speeds to those produced using traditional accelerators – but in a fraction of the distance. Scientists are exploring LPAs as a compact, cost-effective way to generate proton beams, but several technical challenges have hindered their progress.

One challenge arises from the high-intensity laser, which destroys the targets after each pulse, requiring a new target for every shot. Another issue is the beam divergence – proton beams produced by LPAs typically spread out like a floodlight rather than maintaining a narrow focus. Both the need for target replacement and the beam divergence significantly reduce the efficiency of LPA systems.

In this recent study, researchers made an unexpected breakthrough, simultaneously resolving multiple problems although they had only aimed to address one.

QUT researchers created a biosensor using engineered proteins to detect and extract rare earth elements, offering a potential solution to growing demand and environmental challenges.

QUT synthetic biologists have developed a prototype for an innovative biosensor capable of detecting rare earth elements, with the potential for modification to suit various other applications.

Lanthanides (Lns) are essential elements used in electronics, electric motors, and batteries. However, current extraction methods are costly, environmentally damaging, and unable to meet the growing demand.

In a major milestone for particle physics, scientists at CERN’s Large Hadron Collider (LHC) have successfully observed top quarks—one of the most elusive and short-lived fundamental particles—being produced in a laboratory setting. This historic discovery sheds light on the nature of matter and offers new insights into the early Universe, marking a turning point in our understanding of subatomic particles.

Quarks are the fundamental building blocks of protons and neutrons, which in turn make up the atoms forming all matter in the Universe. There are six known types of quarks: up, down, charm, strange, top, and bottom. Among these, the top quark stands out due to its heavy mass and extreme instability.

Unlike protons or neutrons, which persist indefinitely under normal conditions, the top quark decays almost instantly, with a lifetime of just 5×10^−25 seconds. This fleeting existence has made direct observation challenging, making the latest results from the LHC a remarkable breakthrough in experimental physics.