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Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer.

Peter Dempsey, Ph.D., professor of pediatrics– in the CU School of Medicine, and Justin Brumbaugh, Ph.D., assistant professor of molecular, cellular, and developmental biology at CU Boulder, recently published a paper in the journal Nature Cell Biology showing the importance of the H3K36 methylation process in regulating plasticity and regeneration in intestinal cells.

“The intestine has an enormous ability to regenerate itself after injury, and it does this through a model of dedifferentiation,” Dempsey explains. “The cells dedifferentiate back into a type of regenerative stem cell after injury, and those eventually recover the intestine and turn back to normal cells.”

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A note from Lawrence:

I’m excited to announce the third episode of our new series, What’s New in Science, co-hosted by Sabine Hossenfelder. Once again, Sabine and I each brought a few recent science stories to the table, and we took turns introducing them before diving into thoughtful discussions. It’s a format that continues to spark engaging exchanges, and based on the feedback we’ve received, it’s resonating well with listeners.

This time, we covered a wide range of intriguing topics. We began with the latest buzz from the Dark Energy Spectroscopic Instrument suggesting that dark energy might be changing over time. I remain skeptical, but the possibility alone is worth a closer look. We followed that with results from the Euclid space telescope, which has already identified nearly 500 strong gravitational lensing candidates—an impressive yield from just the early data.

Our minds are not hard-wired by age 18. They are changeable through our lives. Hear from people whose brains have changed to overcome disabilities.

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Just as pilots use flight simulators to safely practice complex maneuvers, scientists may soon conduct experiments on a highly realistic simulation of the mouse brain. In a new study, researchers at Stanford Medicine and their collaborators developed an artificial intelligence.

Artificial Intelligence (AI) is a branch of computer science focused on creating systems that can perform tasks typically requiring human intelligence. These tasks include understanding natural language, recognizing patterns, solving problems, and learning from experience. AI technologies use algorithms and massive amounts of data to train models that can make decisions, automate processes, and improve over time through machine learning. The applications of AI are diverse, impacting fields such as healthcare, finance, automotive, and entertainment, fundamentally changing the way we interact with technology.

IN A NUTSHELL 🔬 Toponium discovery at CERN could revolutionize our understanding of particle physics. 📊 The CMS collaboration detected an unexpected excess of top quark-antiquark pairs, hinting at this elusive particle. 🚀 If confirmed, toponium would be the smallest hadron ever discovered, challenging existing theories. 🧩 Researchers aim to refine their models and collaborate