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Protein dynamics play a crucial role in diverse functions. The intracellular environment significantly influences protein dynamics, particularly for intrinsically disordered proteins (IDPs).

A research group led Prof. Zhang Lihua from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS), in collaboration with Assoc. Prof. Gong Zhou from the Precision Measurement Science and Technology Innovation Research Institute of CAS, has proposed a strategy using in-vivo chemical cross-linking and (in-vivo XL-MS) to decode the dynamic structure of proteins within .

In-vivo XL-MS is potential for analyzing the dynamic structure of proteins within cells due to its high throughput, high sensitivity, and low requirements for protein purity.

The most energetic light ever seen emanating from the Sun has just been detected, creating a new puzzle for solar physicists to solve.

A 6-year observing campaign by more than 30 institutions across North America, Europe, and Asia has resulted in the first ever detection of solar gamma radiation in the teraelectronvolt (TeV) range.

But, contrary to what you might expect, it did not correlate to heightened solar activity; or, indeed, any solar activity. Rather, the Sun was pretty calm at the time of the detection, and our current models of the Sun can’t quite account for it.

In 1,846, astronomer and mathematician Urbain Le Verrier sat down and attempted to locate a planet that had never been seen before by humans. Uranus (grow up) had been moving in unexpected ways, as predicted by the Newtonian theory of gravity.

Though the discrepancies were small, there was a difference between the observed orbit of Uranus and the way Newtonian physics predicted its orbit to be. In July, Le Verrier proposed that the difference could be explained by another planet beyond Uranus, and made predictions as to the orbit of this previously unknown body.

Being a mathematician first and an astronomer second, he wasn’t really interested in finding it with a telescope now that he’d found it in maths, and the task of searching for it was left to German astronomer Johann Gottfried Galle. On September 23, 1846, Galle looked at the spot Le Verrier had predicted the planet would be, and found to be within 1 degree of the spot… the planet Neptune.

Topology has become a critical factor in the field of modern condensed matter physics and beyond. It explains the way solid materials may possess two distinct and seemingly conflicting characteristics. An example of this is topological insulators, materials whose bulk acts as an insulator, and can still conduct electricity at their surfaces and edges.

Over the past several decades, the idea of topology has revolutionized the understanding of electronic structure and the overall properties of materials. Additionally, it has opened doors to technological advancements by facilitating the integration of topological materials into electronic applications.

At the same time, topology is quite tricky to measure, often requiring combinations of multiple experimental techniques such as photoemission and transport measurements. A method known as high harmonic spectroscopy has recently emerged as a key technique to observe the topology of a material. In this approach a material is irradiated by intense laser light.

Euclid, a space mission led by the European Space Agency.

The European Space Agency (ESA) is an intergovernmental organization dedicated to the exploration and study of space. ESA was established in 1975 and has 22 member states, with its headquarters located in Paris, France. ESA is responsible for the development and coordination of Europe’s space activities, including the design, construction, and launch of spacecraft and satellites for scientific research and Earth observation. Some of ESA’s flagship missions have included the Rosetta mission to study a comet, the Gaia mission to create a 3D map of the Milky Way, and the ExoMars mission to search for evidence of past or present life on Mars.

Following the path of electronic integrated circuits (EICs), silicon (Si) photonics holds promises to enable photonic integrated circuits (PICs) with high densities, advanced functionality and portability. Although various Si photonics foundries are rapidly developing PIC capabilities—enabling volume production of modulators, photodetectors and most recently lasers—Si PICs have yet to achieve the stringent requirements on laser noise and overall system stability imposed by many applications such as microwave oscillators, atomic physics and precision metrology9,10,11. Semiconductor lasers must strongly suppress amplified-spontaneous-emission noise to achieve narrow linewidth for these applications12. They will also require isolation from the rest of the optical system, otherwise the laser source will be sensitive to back-reflections from downstream optical components that are beyond the control of the PIC designer13. In many integrated photonic solutions, a bulk optical isolator must be inserted between the laser chip and the rest of the system, significantly increasing the complexity, as well as the cost of assembly and packaging14.

To enrich the capabilities of Si PICs and avoid multi-chip optical packaging, non-group-IV materials need to be heterogeneously integrated to enable crucial devices, including high-performance lasers, amplifiers and isolators15,16,17. It has now been widely acknowledged that group III–V materials are required to provide efficient optical gain for semiconductor lasers and amplifiers in Si photonics regardless of the integration architecture, but concerns still remain for a complementary metal–oxide–semiconductor (CMOS) fab to incorporate magnetic materials, which are currently used in industry-standard optical isolators18.

Fortunately, a synergistic path towards ultralow laser noise and low feedback sensitivity exists—using ultrahigh-quality-factor (Q) cavities for lasers that not only reduce the phase noise but also enhance the feedback tolerance to downstream links. These effects scale with the cavity Q and ultrahigh–Q cavities would thus endow integrated lasers with unprecedented coherence and stability19,20. The significance is twofold. First, the direct integration of ultralow-noise lasers on Si PICs without the need for optical isolators simplifies PIC fabrication and packaging. Furthermore, this approach does not introduce magnetic materials to a CMOS fab as isolators are not obligatory for such complete PICs.

Utilizing ultra-high-precision laser spectroscopy on a simple molecule, a team of physicists headed by Professor Stephan Schiller Ph.D. of Heinrich Heine University Düsseldorf (HHU) measured the wave-like vibration of atomic nuclei with an unprecedented level of precision.

In their paper published in the scientific journal Nature Physics.

As the name implies, Nature Physics is a peer-reviewed, scientific journal covering physics and is published by Nature Research. It was first published in October 2005 and its monthly coverage includes articles, letters, reviews, research highlights, news and views, commentaries, book reviews, and correspondence.

journey breaks several laws of physics in order to reach the known limit of the universe, using a spacecraft capable of travelling at any speed.
distance and speed are approximate, giving us an idea of how fast the spacecraft has to travel to move through the vast expanses of the universe.
the way, an AI will explain some important elements of the journey, to give us a more complete picture of what we are seeing.

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(Youtube Library)
Hydra — Huma-Huma.
Eureka — Huma-Huma.
Atlantis — Audionautix.
Reflections — MK2
Angelic Forest — Doug Maxwell_Media Right Productions.
Landing On a Dark Planet — Doug Maxwell_Media Right Productions.

Moon — https://en.wikipedia.org/wiki/Moon.