Lifeboat Foundation

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has developed thyroid hormone (TH)–encapsulated nanoparticles modified with an adipose-homing peptide, which selectively transports TH to adipose tissues. This will advance the treatment of obesity-related medical complications with TH by overcoming the severe adverse effects caused by systemic administration. The new findings are now published in Nature Communications.

Obesity is a major risk factor for multiple life-threatening chronic diseases such as diabetes and cardiovascular and neurodegenerative disorders. TH is an ancient hormone with therapeutic potential for obesity and its related medical complications by promoting energy expenditure. However, despite enormous research efforts in the past decades, clinical trials have failed to demonstrate obvious clinical benefits of chronic systemic administration of TH on weight loss in obese individuals.

Furthermore, due to widespread expression of TH receptors, systemic administration of TH often leads to serious deleterious effects on multiple organs, including tachycardia, heart attack, muscle wasting, and osteoporosis. Skeletal muscle and adipose tissues are thought to be the two major target organs where TH exerts its stimulatory actions on metabolic rate and energy expenditure. However, whether selective delivery of TH to adipose tissues is sufficient to induce weight loss remains unclear.

Professor Juhyuk Lee of the Department of Energy Engineering has developed an elastic triboelectric generator that can be used in the daily lives of frequent movers. The cause of the output reduction of the elastic triboelectric sensor was identified during joint research with Professor Joohun Lee of Hanyang University’s (ERICA campus) Department of Bio-Nanotechnology. Additionally, the professor used graphene to develop a touch sensor with stable output and expand the application of the triboelectric generator. The study is published in the journal Nano Energy.

Along with the rapid growth of various biosensors and wearable devices due to the continuous development of semiconductors and small electronic components, there has been a growing interest in triboelectric generators for use as sensors or energy sources. To use the triboelectric generator in a wearable device, the material that comes into contact with the body must be safe, and the output must be constant despite any deformations caused by movement.

However, the output of conventional elastic triboelectric generators is affected by its change in form. The reason for this relationship was not clearly understood. Similar to previously existing products, there are limitations to precise detection if the output changes along with the change in form, such as stretching.

A fuel cell is an electric power generator that is capable of producing electricity from hydrogen gas while discharging only water as a waste product. It is hoped that this highly efficient clean energy system will play a key role in the adoption of the hydrogen economy, replacing the combustion engines and batteries in automobiles and trucks, as well as power plants.

However, the cost of platinum, which can be up to ~30,000 USD per kg, has been a major limitation, making fuel cell catalysts prohibitively expensive. The production methods of highly-performing catalysts have also been complicated and largely limited. Accordingly, the development of a facile and scalable production method for platinum-based fuel cell catalysts is an urgent challenge, together with enhancing catalytic performance and stability while using a minimum amount of platinum.

To tackle this issue, a research team led by Prof. Sung Yung-Eun and Prof. Hyeon Taeghwan at the Center for Nanoparticle Research (CNR) within the Institute for Basic Science (IBS), South Korea has discovered a novel method for the production of nanocatalysts.

Putting that soda bottle or takeout container into the recycling bin is far from a guarantee it will be turned into something new. Scientists at Rice University are trying to address this problem by making the process profitable.

The amount of plastic waste produced globally has doubled over the past two decades—and plastic production is expected to triple by 2050—with most of it ending up in landfills, incinerated or otherwise mismanaged, according to the Organization for Economic Cooperation and Development. Some estimates suggest only 5% is actually being recycled.

“Waste plastic is rarely recycled because it costs a lot of money to do all the washing, sorting and melting down of the plastics to turn it into a material that can be used by a factory,” said Kevin Wyss, a Rice graduate student and lead author on a study published in Advanced Materials that describes how he and colleagues in the lab of chemist James Tour used their flash Joule heating technique to turn plastic into valuable carbon nanotubes and hybrid nanomaterials.

A research team led by Dr. Yong-hun Kim and Dr. Jeong-Dae Kwon has successfully developed the world’s first neuromorphic semiconductor device with high-density and high-reliability by developing a thin film of lithium-ion battery materials. They achieved this by producing ultra-thin lithium ions, a key material of lithium-ion batteries that have been in the spotlight recently, and combining it with two-dimensional nano-materials. The research team is from the Surface & Nano Materials Division at the Korea Institute of Materials Science (KIMS).

A neuromorphic semiconductor device has synapses and neurons similar to the human brain, which processes and memorizes information. The synaptic device receives signals from neurons and modulates the synaptic weight (connection strength) in various ways to simultaneously process and store information. In particular, the linearity and symmetry of synaptic weights enables various pattern recognition with low power.

Traditional methods for controlling synaptic weights use charge traps between interfaces of heterogeneous materials or oxygen ions. In this case, however, it is difficult to control the movement of ions in the desired direction according to the external electric field. The researchers solved this problem with an artificial intelligence semiconductor device with high density by developing a thin film process while maintaining the mobility of lithium ions according to the external electric field. The thin film—with a thickness of several tens of nanometers—enables fine pattern processing while controlling the thickness of the wafer scale.

Vibrations are the main drivers of a mysterious process in which a liquid flow generates an electric current in the solid below it.

Liquid flowing over a conducting surface is known to produce electric currents, but the mechanism behind this effect has been unclear. New experiments with a single liquid drop dragged over a graphene surface demonstrate that viscous forces at the liquid–solid interface create vibrations, or phonons, in the graphene sheet that drag electrons in the direction of the flow [1]. The researchers verified this “phonon wind” interpretation by observing multiple liquids and by testing graphene surfaces with and without wrinkles. The results could lead to highly sensitive flow sensors or to devices that can harvest electricity from flows.

Researchers have found that water flowing over a material—in particular, carbon nanotubes or graphene—can generate electric currents in the solid. The effect appears in carbon materials because the surfaces are atomically flat and thus allow the liquid to flow largely unobstructed at the liquid–solid boundary, explains Alessandro Siria from the École Normale Supérieure in France. Several models have been proposed to explain the flow-induced currents, often involving charges within the liquid acting on the electrons in the solid. However, experimental uncertainties have prevented researchers from determining which model is best.

Researchers at the University of North Carolina at Chapel Hill Department of Chemistry have engineered silicon nanowires that can convert sunlight into electricity by splitting water into oxygen and hydrogen gas, a greener alternative to fossil fuels.

Fifty years ago, scientists first demonstrated that liquid water can be split into oxygen and hydrogen gas using electricity produced by illuminating a semiconductor electrode. Although hydrogen generated using solar power is a promising form of clean energy, low efficiencies and high costs have hindered the introduction of commercial solar-powered hydrogen plants.

An economic feasibility analysis suggests that using a slurry of electrodes made from nanoparticles instead of a rigid solar panel design could substantially lower costs, making solar-produced hydrogen competitive with fossil fuels. However, most existing particle-based light-activated catalysts, also referred to as photocatalysts, can absorb only ultraviolet radiation, limiting their energy-conversion efficiency under solar illumination.

Some researchers are driven by the quest to improve a specific product, like a battery or a semiconductor. Others are motivated by tackling questions faced by a given industry. Rob Macfarlane, MIT’s Paul M. Cook Associate Professor in Materials Science and Engineering, is driven by a more fundamental desire.

“I like to make things,” Macfarlane says. “I want to make materials that can be functional and useful, and I want to do so by figuring out the basic principles that go into making new structures at many different size ranges.” (Image: Adam Glanzman)

In a new approach to security that unites technology and art, EPFL researchers have combined silver nanostructures with polarized light to yield a range of brilliant colors, which can be used to encode messages.

Cryptography is something of a new field for Olivier Martin, who has been studying the optics of nanostructures for many years as head of the Nanophotonics and Metrology Lab EPFL’s School of Engineering. But after developing some new silver nanostructures in collaboration with the Center of MicroNanoTechnology, Martin and Ph.D. student Hsiang-Chu Wang noticed that these nanostructures reacted to polarized light in an unexpected way, which just happened to be perfect for encoding information.

They found that when polarized light was shone through the nanostructures from certain directions, a range of vivid and easily-identifiable colors was reflected back. These different colors could be assigned numbers, which could then be used to represent letters using the electronic communication standard code ASCII (American Standard Code for Information Interchange). To encode a secret message, the researchers applied a quaternary code using the digits 0, 1, 2 and 3 (as opposed to the more commonly used binary code 0 and 1). The result was a series of four-digit strings composed of different color combinations that could be used to spell out a message, and the method of chromo-encryption was born.