Lifeboat Foundation

Eating nutritious food has been shown time and time again to help improve metabolic health and delay aging. But what the appropriate quantities of these dietary macronutrients are has received somewhat varying results.

To investigate what they might be researchers from Waseda University fed isocaloric diets with varying amounts of protein to mice, and their findings are published in GeroScience. According to the researchers, the animals were found to be metabolically healthier when they were fed moderate protein diets, and these findings could provide insight into developing nutritional interventions as well as to improving metabolic health in people.

Continue reading “Eat Right And You Could Live Longer” »

Former Google engineer and esteemed futurist Ray Kurzweil has made another bold prediction: Immortality is within reach for humans by 2030, thanks to the help of nanorobots. You read that right — humans could potentially live forever, according to Kurzweil.

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Kurzweil, who has a track record of accurate predictions such as foreseeing a computer beating humans in chess by 2000, shared his prediction in a recent YouTube series by tech vlogger Adagio. The 75-year-old computer scientist believes that advancements in genetics, robotics and nanotechnology will allow tiny robots to run through veins, repairing any damage and keeping people alive indefinitely.

Ray Kurzweil is known for making predictions in technology that have come true — and now he is sure humans will reach immortality in our lifetime. He also explains how robots will make it happen.

Researchers have for the first time characterised the molecular mechanism of the early stages of programmed cell death or apoptosis, a process which plays a crucial role in the prevention of cancer.

The study, published today (2 June) in Science Advances, was led by Dr Luke Clifton at the Science and Technology Facilities Council (STFC) ISIS Neutron and Muon Source (ISIS) in Oxfordshire. They worked alongside partners at the University of Umea and European Spallation Source in Sweden.

It is the most recent in a series of research collaborations by this team, investigating the cellular proteins responsible for apoptosis.

The largest conference on aging in the biopharmaceutical industry is set to take place 28 August – 1 September 2023 on-site in Copenhagen and online.

Longevity. Technology: The United Nations report that the proportion of people aged over 65 now outnumber children younger than 5. This substantial surge in the elderly populace presents a formidable healthcare challenge for societies across the globe, and it is evident that comprehensive and transformative approaches aimed at mitigating age-related illnesses and vulnerabilities will play a pivotal role in addressing the health and socioeconomic obstacles associated with an aging society. Once again this year, ARDD – now in its tenth year – is set to feature some of the most foremost experts in longevity, who will impart their latest insights on the process of aging and how we target the aging process to maximise lifespan and healthspan.

At ARDD, leaders in the aging and longevity field will describe the latest progress in the molecular, cellular and organismal basis of aging and the search for interventions, making it one of the must-attend events in the longevity space.

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Continue reading “Resveratrol Extends Lifespan, But Only Under Two Experimental Conditions” »

The mammalian retina is a complex system consisting out of cones (for color) and rods (for peripheral monochrome) that provide the raw image data which is then processed into successive layers of neurons before this preprocessed data is sent via the optical nerve to the brain’s visual cortex. In order to emulate this system as closely as possible, researchers at Penn State University have created a system that uses perovskite (methylammonium lead bromide, MAPbX₃) RGB photodetectors and a neuromorphic processing algorithm that performs similar processing as the biological retina.

Panchromatic imaging is defined as being ‘sensitive to light of all colors in the visible spectrum’, which in imaging means enhancing the monochromatic (e.g. RGB) channels using panchromatic (intensity, not frequency) data. For the retina this means that the incoming light is not merely used to determine the separate colors, but also the intensity, which is what underlies the wide dynamic range of the Mark I eyeball. In this experiment, layers of these MAPbX₃ (X being Cl, Br, I or combination thereof) perovskites formed stacked RGB sensors.

The output of these sensor layers was then processed in a pretrained convolutional neural network, to generate the final, panchromatic image which could then be used for a wide range of purposes. Some applications noted by the researchers include new types of digital cameras, as well as artificial retinas, limited mostly by how well the perovskite layers scale in resolution, and their longevity, which is a long-standing issue with perovskites. Another possibility raised is that of powering at least part of the system using the energy collected by the perovskite layers, akin to proposed perovskite-based solar panels.

Researchers have for the first time characterized a unique molecular mechanism of the early stages of programmed cell death or apoptosis, a process which plays a crucial role in prevention of cancer.

The study, which is published June 2, 2023 in Science Advances, was led by Dr. Luke Clifton at the STFC ISIS Neutron and Muon Source (ISIS) in Oxfordshire, alongside co-lead Professor Gerhard Gröbner at the University of Umeå and partners at the European Spallation Source in Sweden. It is the most recent in a series of research collaborations by this team, investigating the cellular proteins responsible for apoptosis.

Apoptosis is essential for human life, and its disruption can cause cancerous cells to grow and not respond to cancer treatment. In healthy cells, it is regulated by two proteins with opposing roles known as Bax and Bcl-2.

Science can’t stop aging, but it may be able to slow our epigenetic clocks.