Lifeboat Foundation

In this October 13 Learning Lab, Hilary Sherman, a Senior Scientist in the Corning Life Sciences Applications Lab, and Robert Padilla, a Field Application Scientist at Corning, dive into the topic of 3D culture techniques and why these technologies should be a part of any researcher’s repertoire.

Three-dimensional (3D) cultures such as spheroids and organoids are an important part of the research model market, helping to close the gap between cell cultures and animal models. Both organoids and spheroids have been used to create in vivo-like tissue models of cancer subtypes to study novel therapies and to make models for tissue engineering and regenerative medicine studies. But there are some key differences, with important implications for various applications. The right tool for a project is not always obvious. For spheroids and organoids, knowing where the cultures are similar and where they differ will help scientists select the best resource for their projects the first time around.

The idea of postponing or even reversing the ageing process has always fascinated humanity. Some claim that immortality will be possible as little as thirty years from now – but will it just be for the rich?

Our team visited research laboratories working on this objective and interviewed the world’s top researchers in the field. We ask just how long humans might be able to live, and what it could involve.

Continue reading “Frozen Bodies Brought Back to Life? Cryogenics and the Science of Immortality” »

https://www.youtube.com/watch?v=pkY1pR6zmpg

Can artificial intelligence, or AI, make it possible for us to live forever? Or at least, be preserved for posterity? What are the current developments in the fields of artificial intelligence and biotechnology?

Will humanity exist without biological bodies, in the near future? Could humans and AI merge into one being? This documentary explores these questions, and more.

Continue reading “AI and the quest for immortality — are we defeating death?” »

While the bacteria in the intestine are helpful for digesting food and fighting infections, they have long been suspected to play an essential role in triggering rheumatoid arthritis. This chronic inflammatory disorder affects the joints.

Mayo Clinic researchers have discovered a link between an abundance of specific gut bacteria and the triggering of an immune response against a person’s tissue. They also found that this happens even before the clinical symptoms of rheumatoid arthritis appear. They published their findings from the study in Science Advances.

“As we age, our gut bacteria and their byproducts change, which impacts our immune system,” says senior author Veena Taneja, Ph.D., a Mayo Clinic immunologist. There is a known link between imbalances in gut bacteria, aging, and rheumatoid arthritis, but it is challenging to prove this connection in humans. “This research sheds light on the complex relationship between gut microbiota and rheumatoid arthritis.”

Researchers say they have linked shorter telomeres on white blood cells to higher dementia risk, although outside experts say there are limitations to this study.

Driving Forces Behind the Growth in UAE’s Life Sciences Industry: the latest from the Life Sciences Division of Deep Knowledge Group created by Deep Knowledge Group, Aging Analytics Agency, Deep Pharma Intelligence, NeuroTech.com, FemTech Analytics, and Deep Knowledge Analytics:

Population Aging: With the world’s population getting older, the demand for medical services is soaring. The UAE is no exception, and this demographic shift is a key driver of growth in the life sciences sector.

New Machines and Drugs: Constant innovation is driving the development of new treatments and drugs to address previously unmet health needs. This not only enhances patient care but also sparks technological… More.

Continue reading “NeuroTech Analytics” »

US biotech Immunis has developed an “immunomodulatory secretome” technology targeting age-related immune decline. With preclinical studies showing benefit in muscular atrophy, metabolic and vascular function, tissue inflammation, and immune cell function in a range of age-related disease indications, the Californian company is currently engaged in its first in-human clinical trial for muscle atrophy.

Longevity. Technology: The secretome refers to the substances that are secreted (released) by cells – exosomes, micro-vesicles, proteins, growth factors, hormones, cytokines, and other substances. The secretome is known to play a role in helping repair and regenerate our bodies, but these beneficial secreted factors decline with age. Immunis has developed a novel method to isolate secreted cellular factors that benefit immune system development, modulation, and health – and replenish them. To find out more about the company and its technology, we spoke to its Chairman, Dr Hans Keirstead.

Keirstead is a renowned stem cell expert and serial entrepreneur, founding and successfully exiting several biotech companies in the stem cell space. Back in the early days of the field, he became the first neuroscientist in the world to work with human stem cells.

Here’s a quick look at Maria Entraigues Abramson’s presentation at RAADfest 2023 in California. Our Director of Develpoment gives an overview of SRF’s work and misison. You can watch the full presentation by renting the video program for the full event from the Coalition for Radical Life Extension here: https://vimeo.com/ondemand/raadfest2023/

In her full presentation, she highlights that adopting a better lifestyle to enhance our health is always a good idea and we should all do this. She personally advocates for everyone to utilize all scientifically supported resources to achieve optimized health. However, she reminds the audience that the mission of SRF is not about lifestyle changes but to transform the aging process completely, aiming to significantly extend our healthspan by repairing our bodies at a cellular level. SRF’s damage-repair approach will lead to a much longer and healthier lifespan—a feat not yet accomplished, regardless of the excellent care we may take of ourselves through lifestyle changes, supplement intake, etc.

Continue reading “Maria Entraigues Abramson’s abbreviated presentation @RAADfest 2023” »

This video discusses what it would mean to live forever or to have a greatly expanded lifespan. Would we inevitably grow bored with existence? Why do we even want to live longer?

We also discuss the philosophy of the Ship of Theseus as it applies to mind upload or body transfer. If you transfer your mind to a new body, are you still the same person? We conclude that the answer is yes if and only if you experience no discontinuities in consciousness.

Continue reading “How humans will reach beyond biological bodies” »