Lifeboat Foundation

Science: Research suggest that dinosaurs 🦕 🦖 may have influenced how humans age today.

Human aging may have been influenced by millions of years of dinosaur domination according to a new theory from a leading aging expert. The ‘longevity bottleneck’ hypothesis has been proposed by Professor Joao Pedro de Magalhaes from the University of Birmingham in a new study published in BioEssays. The hypothesis connects the role that dinosaurs played over 100 million years with the aging process in mammals.

While some reptiles and amphibians show no significant signs of aging, all mammals—including humans—show a marked aging process.

Continue reading “Research suggests that dinosaurs may have influenced how human beings age” »

The FDA has yet to approve any drugs for life extension. But biotech company Loyal is now a step closer to bringing one to market—for dogs.

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Continue reading “Longevity-Associated Triglycerides” »

High-intensity interval training (HIIT) has become very popular; alternating short periods of intense anaerobic exercise with recovery periods, it is designed to help to decrease body fat, increase strength and endurance, and improve healthspan in protocols that last approximately half an hour.

But these days, even finding half an hour can be tricky – enter CAROL Bike, an exercise bike designed around Reduced Exertion HIIT (REHIT) and AI-personalization, meaning an effective workout can be delivered in just 5 minutes.

Continue reading “Improving healthspan and longevity can be just like riding a bike” »

Yes, if it’s quality life this is good and maybe even use this as an example of helping humans live longer and why not cats?

For the first time, the FDA has indicated a willingness to endorse a longevity drug.

Longevity drugs for our canine companions are moving closer to reality. They also raise questions about what it might mean to succeed.

A new study in mice found limited intakes of one particular essential amino acid slowed the impacts of ageing and even lengthened their lifespan.

Scientists are now wondering if these findings could help people improve their longevity and quality of life.

Isoleucine is one of three branched-chain amino acids we use to build proteins in our bodies. It is essential for our survival, but since our cells can’t produce it from scratch, we have to get it from sources like eggs, dairy, soy protein and meats.

Life expectancy and healthy aging in mice can be determined by a protein present in some cells of the immune system, according to a study published in the journal Cell Reports. When this protein—known as the CD300f immune receptor—is absent, animal models have a shorter life expectancy and suffer from pathologies associated with cognitive decline and premature aging, especially in females.

“Our study indicates that alterations in immune system cells, for instance, in macrophages and microglia, can determine the healthy aging degree in mice,” notes Hugo Peluffo, leader of this study and member of the Faculty of Medicine and Health Sciences and the Institute of Neurosciences (UBneuro) of the University of Barcelona.

Understanding how the CD300f immune receptor —and the myeloid cells of the immune system—can determine by themselves the onset rate of aging-associated pathologies, “will help to better understand this process, and it will contribute to the design of strategies to regulate its action. For instance, using the immune receptor CD300f as a target in biomedicine,” notes the expert. “Also, our team has previously shown that some variants of the CD300f immune receptor could be useful as biomarkers in patients.”

New research suggests that biological age, as indicated by DNA methylation, more significantly impacts cognitive abilities like memory and processing speed than chronological age. This finding could reshape our understanding of aging and cognitive health.