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This is the second part of our ongoing series of articles that discuss the Hallmarks of Aging. Published in 2013, the paper divides aging into a number of distinct categories (“hallmarks”) of damage to explain how the aging process works and how it causes age-related diseases[1].

Today, we will be looking at one of the primary hallmarks, epigenetic alterations.

Describes the epigenetic role in aging, cancer and disease as well as drugs that are targeting the epigenome.

Our epigenome plays a role in aging and also in diseases like cancer and diabetes. Scientists have developed epigenome-targeting cancer drugs.

How did you come to accept that aging was a problem?

#CrowdfundTheCure for #aging at www.lifespan.io

The topic of the gut microbiota is increasingly in the news of late, and its connection with chronic age-related inflammation, known as inflammaging, is becoming increasingly clear.

What is the microbiota?

The microbiota describes the community of symbiotic and pathogenic microorganisms that live in and on all multicellular organisms, and it includes bacteria, archaea, protists, fungi, and viruses. In particular, the gut microbiota and its role in aging and disease have increasingly become of interest to researchers in recent years.

Continue reading “A Healthy Aged Gut Is Similar to a Healthy Young Gut” »

Are AI aliens watching Earth? An immortal machine civilization could already exist and may be BILLIONS of years old, leading expert claims…

Artificial intelligence could already exist elsewhere in the universe and may have been around for billions of years, according to a leading expert.

Continue reading “‘Postbiological’ alien civilisation that survives using AI could exist” »

Telomerase replenishes telomeres, extending the cell’s lifespan. Researchers hope that telomerase enhancement will rejuvenate our organs.

Senolytics have been a hot topic lately. Here’s a primer.

Senolytics reverse aging by killing senescent cells. Researchers have found seven senolytics and are testing them in clinical trials.

Last article (3 of 3) in three part stem cell series.

Stem cell decline goes with aging. With the right growth factors, we can awaken our lazy stem cells to repair our aging organs.