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Archive for the ‘life extension’ category: Page 184

Mar 11, 2022

Bionic eyes: How tech is replacing lost vision

Posted by in categories: cyborgs, life extension, neuroscience, transhumanism

This technology has to translate images into something the human brain can understand. Click the numbers in the interactive image below to find read about how this works.

There are a whole range of conditions, some which are picked up due to the aging process and others which may be inherited, that can cause sight deterioration.

Bionic eyes work by ‘filling in the blanks’ between what the retina perceives and how it is processed in the brain’s visual cortex, that breakdown occurs in conditions which impact the retina. It is largely these conditions which bionic eyes could help treat.

Mar 11, 2022

Scientists “Elated”

Posted by in categories: biotech/medical, genetics, life extension

An international team of researchers claim to have slowed the signs of aging in mice by resetting their cells to younger states, using a genetic treatment.

To the scientists, The Guardian reports, it’s a breakthrough in cell regeneration and therapeutic medicine that doesn’t seem to cause any unexpected issues in mice.

“We are elated that we can use this approach across the life span to slow down aging in normal animals,” said Juan Carlos Izpisua Belmonte, Salk Institute professor and co-corresponding author of a new study published in the journal Nature Aging, in a statement. “The technique is both safe and effective in mice.”

Mar 11, 2022

Topical tissue nano-transfection mediates non-viral stroma reprogramming and rescue

Posted by in categories: biotech/medical, life extension, nanotechnology

Circa 2017


Arrayed nanochannels can be used to controllably transfect and reprogram tissues in vivo for applications in regenerative medicine and cell-based therapies.

Mar 11, 2022

Dr. Kara Spiller, PhD — Immunomodulatory Biomaterials In Regenerative Medicine — Drexel University

Posted by in categories: bioengineering, biotech/medical, education, life extension

Immunomodulatory Biomaterials In Regenerative Medicine — Dr. Kara Spiller-Geisler, Ph.D., Drexel University School of Biomedical Engineering, Science and Health Systems.


Dr. Kara Spiller, PhD (https://drexel.edu/biomed/faculty/core/SpillerKara/) is Associate Professor in the Biomaterials and Regenerative Medicine Laboratory at Drexel University, in Philadelphia.

Continue reading “Dr. Kara Spiller, PhD — Immunomodulatory Biomaterials In Regenerative Medicine — Drexel University” »

Mar 11, 2022

Aging reversed in middle-aged and elderly mice

Posted by in categories: biotech/medical, life extension

A new cellular rejuvenation therapy is reported by scientists at the Salk Institute, which can reverse aspects of aging in mice, without causing cancer or other health problems.

Mar 11, 2022

Juan Carlos Izpisua: ‘Within two decades, we will be able to prevent aging’

Posted by in category: life extension

The leading Spanish scientist talks to EL PAÍS about his new role at the secretive multinational Altos Labs, where he hopes to use cellular rejuvenation to reverse illness and cell deterioration.

Mar 11, 2022

CRISPR On-Off Switch Will Help Unlock the Secrets of Our Immune System

Posted by in categories: biotech/medical, genetics, life extension

Can we turn up—or dial down—their fervor by tweaking their genes?

Enter a new kind of CRISPR. Known mostly as a multi-tool to cut, snip, edit, or otherwise kneecap an existing gene, this version—dubbed CRISPRa—forcibly turns genes on. Optimized by scientists at Gladstone Institutes and UC San Francisco, the tool is counterbalanced by CRISPRi—“i” for “interference,” which, you guessed it, interferes with the gene’s expression.

Though previously used in immortal cells grown in labs, this is the first time these CRISPR tools are rejiggered for cells extracted from our bodies. Together, the tools simultaneously screened nearly 20,000 genes in T cells isolated from humans, building a massive genetic translator—from genes to function—that maps how individual genes influence T cells.

Mar 10, 2022

Hibernation found to naturally stop the aging process

Posted by in category: life extension

What if you were told there was a completely natural way to stop your body from aging? The trick: You’d have to hibernate from September to May each year.

Mar 9, 2022

Cellular ‘Rejuvenation’ Experiment in Mice Reverses Signs of Aging, Scientists Say

Posted by in categories: biotech/medical, life extension

With age comes experience. And with experience come sore backs, tired bones, and increased risks from a large number of diseases.

Scientists have long been trying figure out how to stop these aches and pains in our twilight years, and to make us live longer and healthier lives at the same time.

While it’s likely a long way off from being ready for humans, a new study investigating the long-term ‘partial reprogramming’ of cells in mice appears to have produced some very intriguing results.

Mar 7, 2022

Anti-aging molecules safely reset mouse cells to youthful states

Posted by in categories: biotech/medical, chemistry, genetics, life extension, neuroscience

One of the especially promising therapies to appear in the realm of anti-aging research involves a set of molecules known as Yamanaka factors, which scientists have deployed to rejuvenate aging cells, trigger muscle regeneration and tackle glaucoma. New research at the Salk Institute has sought to build on these short-term and specific use cases by demonstrating how these molecules can reverse signs of aging in middle-aged and elderly mice, with no evidence of health problems following the extended treatment.

The Yamanaka factors at the center of this study are a set of four reprogramming molecules that can reset the molecular clock found in the cells of the body. They do so by returning unique patterns of chemicals known as epigenetic markers, which evolve through aging, to their original states.

Continue reading “Anti-aging molecules safely reset mouse cells to youthful states” »