Great article by the great Steve Hill. One little thing:
“The life extension community unfortunately does have a reputation for being long on promises and short on delivery. With what is now decades of research, there are still no effective therapies against aging.”
Continue reading “Life Extension and Anti-Aging Have a Branding Problem” »
Mayo Clinic researchers have proposed a new model for mapping the symptoms of Alzheimer’s disease to brain anatomy. This model was developed by applying machine learning to patient brain imaging data. It uses the entire function of the brain rather than specific brain regions or networks to explain the relationship between brain anatomy and mental processing. The findings are reported in Nature Communications.
“This new model can advance our understanding of how the brain works and breaks down during aging and Alzheimer’s disease, providing new ways to monitor, prevent and treat disorders of the mind,” says David T. Jones, M.D., a Mayo Clinic neurologist and lead author of the study.
Alzheimer’s disease typically has been described as a protein-processing problem. The toxic proteins amyloid and tau deposit in areas of the brain, causing neuron failure that results in clinical symptoms such as memory loss, difficulty communicating and confusion.
Tuberculosis (TB) is a potentially serious infectious disease caused by a type of bacterium called Mycobacterium tuberculosis. The bacteria usually affect the lungs, but also can invade other organs.
In 2018, tuberculosis bacteria infected 1.7 billion people — roughly 23% of the world’s population, according to the Centers for Disease Control and Prevention (CDC). In 2020, the CDC reported 7,174 TB cases and 13 million people living with a latent tuberculosis infection (the germs are in the body but do not cause sickness) in the United States.
Even after successful therapy for tuberculosis, survivors of the disease have an increased risk of recurrent infection and death. A new study published recently by researchers at Baylor College of Medicine found that the cells of humans and animals who have recovered from tuberculosis had prematurely aged up to 12 to 14 years.
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Levine’s Biological age calculator is embedded as an Excel file in this link from my website:
https://michaellustgarten.com/2019/09/09/quantifying-biological-age/
Continue reading “Blood Test #2 in 2022: Supplements, Cardiovascular Fitness Metrics (HRV, RHR)” »
Boston medical researchers in a new groundbreaking study have discovered a “vicious cycle” between daytime napping and Alzheimer’s dementia.
The Brigham and Women’s Hospital researchers found a link between the two: Excessive daytime napping predicted an increased future risk of Alzheimer’s dementia, and a diagnosis of Alzheimer’s dementia sped up the increase in daytime napping during aging.
Daytime napping is common among older adults, but researchers have not known the relationship between daytime napping and cognitive aging.
How Will Nanotechnologies Transform Humanity?
#WomenOfImpact #Nanotech #WeLoveScience #Immortality
Technique allows researchers to toggle on individual genes that regulate cell growth, development, and function.
By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical “off switches” that silence them. Researchers from the University of Washington School of Medicine in Seattle describe this finding in the journal Cell Reports.
The approach will allow researchers to understand the role individual genes play in normal cell growth and development, in aging, and in such diseases as cancer, said Shiri Levy, a postdoctoral fellow in UW Institute for Stem Cell and Regenerative Medicine (ISCRM) and the lead author of the paper.
A new study of an ancient Roman tomb might have uncovered the secret to Roman concrete’s longevity. Turns out it could have a secret ingredient.
Summary: Oleic acid produced in the brain is an essential regulator of processes that enable memory, learning, and mood regulation. Oleic acid, which is abundant in olive oil, also promoted neurogenesis and increases cell proliferation.
Source: Baylor College of Medicine.
Many people dread experiencing the cognitive and mood declines that often accompany reaching an advanced age, including memory disorders such as Alzheimer’s disease and mood conditions like depression.
