Lifeboat Foundation

The maniacally focused founder of Insilico Medicine is going all in on AI to discover new medicines and extend lifespan.

But researchers are now using artificial intelligence to accelerate parts of that process by orders of magnitude. The same kind of technology that recognizes your face or autocompletes your emails can potentially add years to your life, experts say.

2022 https://cryonics.org/wp-content/uploads/2022/11/CI_NEWS-2022-03.pdf.

This issue features:
* President’s Report — New Science Advisory Board.
* 2022 AGM Photos.
* Board of Directors Winners.
* Scale Model CI Cryostats for Sale.
* Cryonics Survey.
* Robert Ettinger’s YOUNIVERSE — Chapter 5
* Latest Cryonics & Life Extension News from Around the Web.

Sea anemones are seemingly immortal animals. They seem to be immune to aging and the negative impacts that humans experience over time. However, the exact reasons for their eternal youth are not completely understood.

The genetic fingerprint of the sea anemone Nematostella vectensis reveals that members of this incredibly ancient animal phylum employ the same gene cascades for neural cell differentiation as more complex organisms. These genes are also in charge of maintaining the balance of all cells in the organism during the anemone’s lifetime. These findings were recently published in the journal Cell Reports by a group of developmental biologists headed by Ulrich Technau of the University of Vienna.

Almost all animal organisms are made up of millions, if not billions, of cells that join together in intricate ways to create specific tissues and organs, which are made up of a range of cell types, such as a variety of neurons and gland cells. However, it is unclear how this critical balance of diverse cell types emerges, how it is regulated, and if the different cell types of different animal organisms have a common origin.

University of Missouri researchers made the discovery while using bioluminescent imaging technology to study how nicotinamide riboside supplements work inside the body.

Commercial dietary supplements like nicotinamide riboside (NR), a form of vitamin B3, were linked to benefits related to cardiovascular, metabolic, and neurological health in previous studies. However, new research from the University of Missouri (MU) has found NR could actually increase the risk of serious disease, including developing cancer.

Supplements containing nicotinamide riboside are often marketed as NAD+ boosters claimed benefits including increased energy, anti-aging/longevity/healthy aging, improved cellular energy metabolism and repair, increased vitality, and improved heart health.

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Continue reading “Longitudinal Biomarker Optimization: A Road To Maximize Health And Longevity?” »

Longevity is not yet considered an official medical term, and aging is not officially considered a disease but a natural occurrence in every living thing.

However, some biologists, researchers and practicing doctors believe this approach should change, and they are striving to discover the mechanisms of aging in humans. In doing so, they are creating age clocks by defining biomarkers for measuring biological age, exploring the best lifestyle habits and natural supplements, and inventing new drugs that could stop us from getting older.

Longevity has been on the radar of crypto leaders for some time already, which is not a surprise given that the industry promises to improve humankind through innovation. Indeed, one prominent event in the longevity industry, the Longevity Investors Conference, is organized by Marc P. Bernegger and Tobias Reichmuth, who were previously involved with the Crypto Finance Group.

Ever wonder why some 90-year olds don’t seem to slow down and seem. to retain the mental and physical capacity of someone half their age?
Do they have good genes? Or is there a way that all of us can get older without getting old?

That’s what Dr. Nir Barzilai, founder of the Institute for Aging Research at the Albert Einstein College of Medicine, set out to answer in his book, Age Later.

Continue reading “A discussion with Dr. Nir Barzaili on Age Later” »

Summary: The epigenetic clocks of those who indulged in unhealthy behaviors as teens were 1.7 to 3.3 years older than individuals who reported more healthy lifestyles as teens.

Source: eLife.

Biological aging results from damage to cells and tissues in the body that accumulates over time. The results of the study could lead to new ways of identifying young people at risk of developing unhealthy habits that are associated with accelerated biological aging and suggest interventions to prevent poor health outcomes later on.

Scientists at the University of Pittsburgh School of Medicine have discovered the missing puzzle piece in the mystery of how melanoma tumors control their mortality.

In a paper published in Science this week, Jonathan Alder, Ph.D. and his team describe how they discovered the perfect combination of genetic alterations that tumors use to promote explosive growth and prevent their own demise, a development that could change the way oncologists understand and treat melanoma.

“We did something that was, in essence, obvious based on previous basic research and connected back to something that is happening in patients,” said Alder, assistant professor in the Division of Pulmonary, Allergy and Critical Care Medicine at Pitt’s School of Medicine.