Lenacapavir, a twice yearly injection that prevents HIV transmission, was named the breakthrough medicine of 2024. But without US foreign aid dollars, its delivery to millions worldwide is under threat.
Category: innovation – Page 4
Two heads are better than one, as the saying goes, and sometimes two instruments, ingeniously recombined, can accomplish feats that neither could have done on its own.
Such is the case with a hybrid microscope, born at the Marine Biological Laboratory (MBL), that for the first time allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The research is published this week in Proceedings of the National Academy of Sciences.
The microscope combines polarized fluorescence technology, a valuable tool for measuring the orientation of molecules, with a dual-view light sheet microscope (diSPIM), which excels at imaging along the depth (axial) axis of a sample.
Scientists have developed Rhobo6, a light microscopy probe that reveals extracellular matrix structures in live tissues, advancing biological research and disease diagnostics.
Rhobo6 is a light microscopy probe that selectively binds to extracellular matrix glycans, increasing its fluorescence and allowing clear visualization of these structures in live tissues. This innovative tool enables researchers to study the extracellular matrix in detail without disrupting native biological processes, offering new insights into tissue biology and disease.
Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical instruments like microscopes and spectrometers.
British physician and microbiologist Alexander Fleming, discoverer of penicillin nearly 100 years ago, was the first to warn of the dangers of antibiotic resistance.
In his 1945 Nobel Prize speech, 27 years after his breakthrough discovery, Fleming put the world on notice foretelling a potentially dark future for his miracle drug in the event of abuse or overuse of the medication. It was a warning that spelled trouble ahead for a vast segment of the pharmacopeia known as antimicrobial drugs.
Now, microbiologists in Hungary and China are collaborating on ways to predict drug resistance among strains of Staphylococcus aureus when exposed to antibiotics in the drug development pipeline—drugs that have yet to reach the marketplace.
Intel’s 18A Process Reportedly Comes With SRAM Density On-Par With TSMC’s N2; Team Blue Gearing Up For A Phenomenal Comeback
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Intel’s 18A is said to report an SRAM density equal to that of TSMC’s N2 process, signaling a massive breakthrough for the IFS and its semiconductor ambitions.
Intel’s 18A Process Is a “Special” One, Credits To Implementations Such As BSPDN Along With Years of R&D Behind It
Well, it seems like now might be the time to be bullish on the future of Intel’s chip plans, since the latest reports are clearly indicating that the momentum is shifting towards Team Blue. Following the political backing of the Trump administration, it is now disclosed via ISSCC sessions (via Ian Cutress) that both TSMC and Intel’s cutting-edge processes are rivaling each other in SRAM densities, showing that the gap has been narrowed down significantly, at least in one of the important aspects.
A team of scientists in France sustained an artificial sun for 22 minutes, which in the future could potentially provide unlimited clean energy.
Elad Harel is used to shining a light on the mysteries of the natural world.
Working at the cutting edge of ultrafast spectroscopy—the use of short laser pulses to analyze molecular dynamics—the Michigan State University associate professor seeks to uncover how microscopic phenomena impact large complex systems.
One promising frontier Harel has been working on is the development of new methods of microscopy that will allow researchers to observe molecular and atomic landscapes in motion rather than through static imagery. Such work has earned Harel MSU’s 2023 Innovation of the Year award, as well as MSU’s first-ever grant from the W.M. Keck Foundation.
The key breakthrough? Finding a gene small enough to fit inside a viral delivery system. Early results in lab models suggest this therapy could be a game-changer, but further research is needed before it reaches clinical trials.
The Urgent Need for Better Arrhythmia Treatments
Cardiac arrhythmias affect millions worldwide and contribute to one in five deaths in the Netherlands. Current treatment options range from lifelong medication to invasive surgeries. However, new research from Amsterdam UMC and Johns Hopkins University, published today (February 20) in the European Heart Journal, marks a significant step toward a potential one-time gene therapy that could enhance heart function and prevent arrhythmias.
Will the dream of interstellar travel soon become reality? Experts have been working for some time on concepts that will one day enable us to enter foreign star systems. Until now, the vast expanses of space have always thwarted this ambitious desire – after all, even the Alpha Centauri system, which is only 4.34 light-years away, is tens of thousands of travel years away with our current means! But now NASA has presented a revolutionary propulsion technology that should get us to the star system of our dreams in just 40 years! But how does the groundbreaking Sunbeam drive work? What technical tricks will make the vast distances of the cosmos seem forgotten – and when will the first interstellar research probe leave Earth?
It’s a breakthrough in cancer treatment, and UChicago Medicine is one of the first hospitals to offer it.
It’s not just one treatment, but can eventually become a whole new way to treat cancer.
Alla Pinzour has been fighting skin cancer for around 15 years—but not anymore.