Lifeboat Foundation

Mount Sinai researchers have designed an innovative experimental therapy that may be able to stop the growth of triple-negative breast cancer, the deadliest type of breast cancer, which has few effective treatment options, according to a study published in Nature Chemical Biology in December.

The therapy is known is MS1943. In a cancer cell line and mouse models, it degraded a protein called EZH2 that drives the growth of triple-negative breast cancer.

Research teams led by Jian Jin, Ph.D., Director of the Mount Sinai Center for Therapeutics Discovery, and Ramon Parsons, MD, Ph.D., Director of The Tisch Cancer Institute at Mount Sinai, developed MS1943 as a first-in-class small-molecule agent that selectively degrades EZH2. They also showed that agents that inhibit the enzymatic activity of EZH2 but do not degrade EZH2 did not work in triple-negative breast cancer.

Superpowerful lasers for next-generation technologies are closer to existence.

Millions of people need new corneas. In a major breakthrough, researchers can now 3D print them.

The innovative technology used to settle on the Red Planet will prove to be very useful on our own homeworld.

Scientists have discovered yet another life-giving treatment for disease using adult stem cells, while the number of substantial medical breakthroughs from life-taking embryonic stem cell research remains essentially zero.

Neuromyelitis optica (NMO), also known as Devic’s disease, causes the immune system to react against the body’s own cells in the central nervous system, particularly the eyes and spinal cord. Those who contract the disease usually lose their eyesight and ability to walk within five years.

Continue reading “Another adult stem cell breakthrough” »

Facebook AI research’s latest breakthrough in natural language understanding, called XLM-R, performs cross-language tasks with 100 different languages including Swahili and Urdu, but it’s also running up against the limits of existing computing power.

Scientists at Harvard have created a texture in meat grown in a lab close to the actual animal meat we’re used to. Would you eat it?
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Human meat consumption is bad for the planet—livestock raised for food makes up for approximately 14–18% of our greenhouse gas emissions, and the land requirements to grow their food is responsible for nearly 80% of all deforestation in the Amazon.

Continue reading “This Breakthrough in Lab-Grown Meat Could Make it Look Like Real Flesh” »

Researchers are designing a stingray-shaped spacecraft to explore the dark side of Venus.

(Image: © CRASH Lab, University at Buffalo)

Could a stingray-shaped spacecraft get to the dark side of Venus by flapping its wings?

Continue reading “This Stingray-Shaped Spacecraft Could Be Perfect For Exploring Venus’ Dark Side” »

Innovative nanosheets made from equal parts of hydrogen and boron have a greater capacity to store and release hydrogen compared with conventional metal-based materials.