Lifeboat Foundation

Engineers sometimes turn to nature for inspiration. Cold Spring Harbor Laboratory Associate Professor Saket Navlakha and research scientist Jonathan Suen have found that adjustment algorithms—the same feedback control process by which the Internet optimizes data traffic—are used by several natural systems to sense and stabilize behavior, including ant colonies, cells, and neurons.

Internet engineers route data around the world in small packets, which are analogous to ants. As Navlakha explains, “The goal of this work was to bring together ideas from machine learning and Internet design and relate them to the way ant colonies forage.”

The same algorithm used by internet engineers is used by ants when they forage for food. At first, the colony may send out a single ant. When the ant returns, it provides information about how much food it got and how long it took to get it. The colony would then send out two ants. If they return with food, the colony may send out three, then four, five, and so on. But if ten ants are sent out and most do not return, then the colony does not decrease the number it sends to nine. Instead, it cuts the number by a large amount, a multiple (say half) of what it sent before: only five ants. In other words, the number of ants slowly adds up when the signals are positive, but is cut dramatically lower when the information is negative. Navlakha and Suen note that the system works even if individual ants get lost and parallels a particular type of “additive-increase/multiplicative-decrease algorithm” used on the internet.

Quanta Magazine.

In The Structure of Scientific Revolutions, the philosopher of science Thomas Kuhn observed that scientists spend long periods taking small steps. They pose and solve puzzles while collectively interpreting all data within a fixed worldview or theoretical framework, which Kuhn called a paradigm. Sooner or later, though, facts crop up that clash with the reigning paradigm. Crisis ensues. The scientists wring their hands, reexamine their assumptions and eventually make a revolutionary shift to a new paradigm, a radically different and truer understanding of nature. Then incremental progress resumes.

For several years, the particle physicists who study nature’s fundamental building blocks have been in a textbook Kuhnian crisis.

Continue reading “Crisis in Particle Physics Forces a Rethink of What Is ‘Natural’” »

Is the Chief Medical Officer at Current Health (https://currenthealth.com/), a Best Buy Health company (https://healthcare.bestbuy.com/) and part of the American multinational consumer electronics retailer.

Current Health is an organization that enables the delivery of healthcare services in the home to enable healthcare organizations to deliver high-quality, patient-centric care at a lower cost. The company integrates patient-reported data with data from biosensors – including their own continuous monitoring wearable devices – to provide healthcare organizations with actionable, real-time insights into the patient’s condition. Leveraging clinical algorithms that can be tailored to the individual patient, Current Health identifies when a patient needs clinical attention, allowing organizations to manage patient care remotely or coordinate in-home care via integrated service partners. The Current Health platform brings together tele-health capabilities, patient engagement tools, and in-home connectivity to provide a single solution to manage all care in the home. Dr. Wolfberg also leads implementation and account management at the organization.

Continue reading “Dr. Adam Wolfberg, MD, MPH — Chief Medical Officer, Current Health — Quality Healthcare In The Home” »

Researchers from the University of Oxford’s Big Data Institute have taken a major step towards mapping the entirety of genetic relationships among humans: a single genealogy that traces the ancestry of all of us. The study has been published today in Science.

Imagine a field of wheat that extends to the horizon, being grown for flour that will be made into bread to feed cities’ worth of people. Imagine that all authority for tilling, planting, fertilizing, monitoring and harvesting this field has been delegated to artificial intelligence: algorithms that control drip-irrigation systems, self-driving tractors and combine harvesters, clever enough to respond to the weather and the exact needs of the crop. Then imagine a hacker messes things up.

Imagine a field of wheat that extends to the horizon, being grown for flour that will be made into bread to feed cities’ worth of people. Imagine that all authority for tilling, planting, fertilizing, monitoring and harvesting this field has been delegated to artificial intelligence: algorithms that control drip-irrigation systems, self-driving tractors and combine harvesters, clever enough to respond to the weather and the exact needs of the crop. Then imagine a hacker messes things up.

A new risk analysis, published today in the journal Nature Machine Intelligence, warns that the future use of artificial intelligence in agriculture comes with substantial potential risks for farms, farmers and food security that are poorly understood and under-appreciated.

“The idea of intelligent machines running farms is not science fiction. Large companies are already pioneering the next generation of autonomous ag-bots and decision support systems that will replace humans in the field,” said Dr. Asaf Tzachor in the University of Cambridge’s Center for the Study of Existential Risk (CSER), first author of the paper.

With the advent of Big Data, current computational architectures are proving to be insufficient. Difficulties in decreasing transistors’ size, large power consumption and limited operating speeds make neuromorphic computing a promising alternative.

Neuromorphic computing, a new brain-inspired computation paradigm, reproduces the activity of biological synapses by using artificial neural networks. Such devices work as a system of switches, so that the ON position corresponds to the information retention or “learning,” while the OFF position corresponds to the information deletion or “forgetting.”

In a recent publication, scientists from the Universitat Autònoma de Barcelona (UAB), the CNR-SPIN (Italy), the Catalan Institute of Nanoscience and Nanotechnology (ICN2), the Institute of Micro and Nanotechnology (IMN-CNM-CSIC) and the ALBA Synchrotron have explored the emulation of artificial synapses using new advanced material devices. The project was led by Serra Húnter Fellow Enric Menéndez and ICREA researcher Jordi Sort, both at the Department of Physics of the UAB, and is part of Sofia Martins Ph.D. thesis.

In the field of optogenetics, scientists investigate the activity of neurons in the brain using light. A team led by Prof. Dr. Ilka Diester and Dr. David Eriksson from the Optophysiology Laboratory at the University of Freiburg has developed a new method to simultaneously conduct laminar recordings, multifiber stimulations, 3D optogenetic stimulation, connectivity inference, and behavioral quantification on brains. Their results are presented in Nature Communications. “Our work paves the way for large-scale photo-recording and controlled interrogation of fast neural communication in any combination of brain areas,” Diester explains. “This can help us unravel the rapid and multilayered dialogs between neurons that maintain brain function.”

The research group, in collaboration with Dr. Patrick Ruther of the Department of Microsystems Engineering (IMTEK) at the University of Freiburg, is developing a new method for the controlled interrogation and recording of neuronal activity in the brain. To do this, the team is taking advantage of thin, cell-sized optical fibers for minimally invasive optogenetic implantation. “We combine side-emitting fibers with silicon probes to achieve high-quality recordings and ultrafast, multichannel optogenetic control.”

They call the system Fused Fiber Light Emission and eXtracellular Recording, or FFLEXR. In addition to optical fibers that can be attached to any silicon probe, the team uses linear depth-resolved stimulation, a lightweight fiber matrix connector, a flexible multifiber ribbon cable, an optical commutator for efficient multichannel stimulation, a general-purpose patch cable, and an algorithm to manage the photovoltaic response.