Lifeboat Foundation

I never get tired in circuitry thread and any new findings.

Tufts University engineers say that revolutionary health diagnostics may be hanging on a thread—one of many threads they have created that integrate nano-scale sensors, electronics and microfluidics into threads ranging from simple cotton to sophisticated synthetics. “We think thread-based devices could potentially be used as smart sutures for surgical implants, smart bandages to monitor wound healing, or integrated with textile or fabric as personalized health monitors and point-of-care diagnostics,” says Sameer Sonkusale, Ph.D., director of the interdisciplinary Nano Lab in the Department of Electrical and Computer Engineering at Tufts School of Engineering, Medford/Somerville, Mass.

Researchers dipped a variety of conductive threads in physical and chemical sensing compounds and connected them to wireless electronic circuitry. The threads, sutured into tissues of rats, collected data on tissue health (pressure, stress, strain and temperature), pH and glucose levels. The data helps determine how wounds are healing, whether infection is emerging or whether the body’s chemistry is out of balance. Thread’s natural wicking properties draw fluids to the sensing compounds. Resulting data is transmitted wirelessly to a cell phone and computer.

Continue reading “Smarter thread” »

If the 1967 film “The Graduate” were remade today, Mr. McGuire’s famous advice to young Benjamin Braddock would probably be updated to “Plastics … with nanoparticles.” These days, the mechanical, electrical and durability properties of polymers—the class of materials that includes plastics—are often enhanced by adding miniature particles (smaller than 100 nanometers or billionths of a meter) made of elements such as silicon or silver. But could those nanoparticles be released into the environment after the polymers are exposed to years of sun and water—and if so, what might be the health and ecological consequences?

In a recently published paper, researchers from the National Institute of Standards and Technology (NIST) describe how they subjected a commercial nanoparticle-infused coating to NIST-developed methods for accelerating the effects of weathering from ultraviolet (UV) radiation and simulated washings of rainwater. Their results indicate that humidity and exposure time are contributing factors for nanoparticle release, findings that may be useful in designing future studies to determine potential impacts.

In their recent experiment, the researchers exposed multiple samples of a commercially available polyurethane coating containing silicon dioxide nanoparticles to intense UV radiation for 100 days inside the NIST SPHERE (Simulated Photodegradation via High-Energy Radiant Exposure), a hollow, 2-meter (7-foot) diameter black aluminum chamber lined with highly UV reflective material that bears a casual resemblance to the Death Star in the film “Star Wars.” For this study, one day in the SPHERE was equivalent to 10 to 15 days outdoors. All samples were weathered at a constant temperature of 50 degrees Celsius (122 degrees Fahrenheit) with one group done in extremely dry conditions (approximately 0 percent humidity) and the other in humid conditions (75 percent humidity).

Continue reading “‘Sun and rain’ detail how nanoparticles can escape from plastic coatings into the environment” »

MIT researchers have designed nanosensors that can profile tumors and may yield insight into how they will respond to certain therapies. The system is based on levels of enzymes called proteases, which cancer cells use to remodel their surroundings.

Once adapted for humans, this type of sensor could be used to determine how aggressive a tumor is and help doctors choose the best treatment, says Sangeeta Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science and a member of MIT’s Koch Institute for Integrative Cancer Research.

“This approach is exciting because people are developing therapies that are protease-activated,” Bhatia says. “Ideally you’d like to be able to stratify patients based on their protease activity and identify which ones would be good candidates for these therapies.”

Continue reading “Nanosensors help understand how tumors will respond to therapies” »

Please sign this petition to the NIH to help get more funding for aging research.

Every year about two million Americans die of illnesses doctors cannot cure. Cancer afflicts 50% of men and 30% of women. Five hundred and ninety five thousand Americans will die of cancer this year. Millions get heart diseases, strokes, etc. Every year 1,612,552 Americans die of the top 8 illnesses that doctors are unable to cure. Over a 30-year period, 48,376,560 United States citizens will die of the top 8 illnesses. Let us not forget other disabling and potentially curable illnesses. How much is it worth to save them? We have the resources and opportunity to cure age-related disease.

History has shown that medical research actually saves money. We now spend three trillion two hundred billion dollars yearly for health care. The health care expenditures will increase as our population grows with more senior citizens.

Continue reading “Fund Medical Research to End Age-Related Disease” »

Crohn’s Disease is a legendarily difficult disease to not only identify but to treat or cure. The disease affects the intestines and digestive tract, stemming from bacteria in those areas building up and leading to serious side effects. It affects more than half a million people in the United States and is brutal – with the possibility of diarrhea, weight loss, fatigue, ulcers, malnutrition, and eventually colon cancer, liver disease or osteoporosis.

Treatment is limited, with the current best options being medicine to limit inflammation and prevent symptoms. There is no complete cure, only efforts to make life as comfortable and normal as possible for those afflicted. Without a specific target at which to aim some sort of treatment, the options for permanently reducing or removing symptoms and health risks are few and far between. Before now, the only thing scientists thought they knew about the disease’s cause was that E Coli was involved.

However, recent studies have led researches to believe that they have narrowed down other bacteria that contributes to the onset and ongoing symptoms of Crohn’s. Experts at the Center for Medical Mycology at Case Western Reserve and University Hospitals Cleveland Medical Center (wow, is that a mouthful!) think they have pinpointed two additional bacterial strains that contribute to the disease. They studied a cross section of people – those with the disease, those with the disease whose family members did not have it, and those without it – to attempt to identify common details in their biological tests. Such a diverse group of subjects is required not only due to the importance of adhering to the scientific method but because Crohn’s can be caused by genetics and environmental factors.

https://youtube.com/watch?v=ldFFJRdhVs8

You can make your own medical device or pay full price for the patented product.

These days there are a quite a few high-tech ways to keep our oral hygiene in check, from toothbrushes that track your technique to smart floss dispensers that encourage healthy habits. Mint is the latest connected solution to hit bathrooms and beyond, and is said to detect signs of gum disease and poor oral hygiene on your breath in the space of a few seconds.

Developed by Breathometer, the same company behind the smartphone-based breathalyzer we covered back in 2013, Mint is small handheld device that hooks up with iOS and Android smartphones to check in on the state of affairs inside your mouth. After a successful Indiegogo campaign in March 2015 and some good attention at the CES conference that same year, the device has finally started shipping today.

A sensor array inside the device measures the volatile sulfur compounds (VSCs) in your breath. Studies have shown these to be key culprits behind bad breath, but their presence might do more than send your significant other running in the other direction. They can also be indicative of gum disease and poor oral health.

Improved autonomous vehicle technology could reduce the tens of thousands of annual U.S. deaths due to human error behind the wheel. Are driverless cars the next big public health intervention?

This computational illustration shows a graphene network structure below a layer of water.

New analysis finds way to safely conduct heat from graphene to biological tissues.

Continue reading “MIT: Powering up graphene implants without frying cells ~ For the Next Generation of Implants” »