Lifeboat Foundation

Scientists looking to tackle our ongoing obesity crisis have made an important discovery: Intermittent fasting leads to significant changes both in the gut and the brain, which may open up new options for maintaining a healthy weight.

Researchers from China studied 25 volunteers classed as obese over a period of 62 days, during which they took part in an intermittent energy restriction (IER) program – a regime that involves careful control of calorie intake and fasting on some days.

Not only did the participants in the study lose weight – 7.6 kilograms (16.8 pounds) or 7.8 percent of their body weight on average – there was also evidence of shifts in the activity of obesity-related regions of the brain, and in the make-up of gut bacteria.

An Indian researcher led a team that developed a rice variety that takes up less arsenic and they’re now working on one that will generate less greenhouse gas emissions.

According to the World Health Organization, an estimated 140 million people in over 70 countries drink water containing the toxic element arsenic at levels above WHO guidelines and in the Indian subcontinent, contaminated water from the Himalayas flow down across multiple countries into farmlands and irrigation reservoirs, which are then absorbed by food crops like rice, the dominant dietary staple in the region.

Jauhar Ali, head of the Hybrid Rice Development Consortium (HRDC), at the International Rice Research Institute (IRRI) says that in 2012, he and his team identified that arsenic toxicity was a key rice production constraint in India and Bangladesh.

In the realm of culinary innovation, Japan has once again captured the spotlight with a groundbreaking invention. Imagine savoring your favorite low-sodium dishes, but with the rich salty flavor. This is no longer a fantasy, thanks to the ingenious creation of the ’ Electric Salt ’ bowl and spoon by scientists at Kirin Holdings Company and Meiji University in Japan (Figure 1).

Launched this year in Japan, the ‘Electric Salt’ devices are more than just ordinary kitchenware. They employ a subtle electrical stimulation, amplifying the salty taste of foods by an astonishing 1.5 times, all without the health drawbacks of high sodium intake. This revolutionary technology promises a new horizon for those mindful of their salt consumption, without sacrificing flavor.

This ingenious mechanism allows a minuscule electric current to pass through the food, enhancing the sodium ions’ journey to the diner’s taste buds. This process remarkably intensifies the salty flavor without any known impact on human health.

The UK’s supreme court has ruled that AI cannot be named as an inventor and secure patent rights. It follows earlier decisions from lower courts that reached the same conclusions.

On Wednesday, US computer scientist Stephen Thaler lost his attempt to register patents for inventions he says were created by his AI system, DABUS.

Thaler said DABUS autonomously created a light beacon and a container for food and drink, and entitled to rights over the inventions.

2023 was the year that CRISPR gene-editing sliced its way out of the lab and into the public consciousness—and American medical system. The Food and Drug Administration recently approved the first gene-editing CRISPR therapy, Casgevy (or exa-cel), a treatment from CRISPR Therapeutics and partner Vertex for patients with sickle cell disease. This comes on the heels of a similar green light by U.K. regulators in a historic moment for a gene-editing technology whose foundations were laid back in the 1980s, eventually resulting in a 2020 Nobel Prize in Chemistry for pioneering CRISPR scientists Jennifer Doudna and Emmanuelle Charpentier.

That decades-long gap between initial scientific spark, widespread academic recognition, and now the market entry of a potential cure for blood disorders like sickle cell disease that afflict hundreds of thousands of people around the world is telling. If past is prologue, even newer CRISPR gene-editing approaches being studied today have the potential to treat diseases ranging from cancer and muscular dystrophy to heart disease, birth more resilient livestock and plants that can grapple with climate change and new strains of deadly viruses, and even upend the energy industry by tweaking bacterial DNA to create more efficient biofuels in future decades. And novel uses of CRISPR, with assists from other technologies like artificial intelligence, might fuel even more precise, targeted gene-editing—in turn accelerating future discovery with implications for just about any industry that relies on biological material, from medicine to agriculture to energy.

With new CRISPR discoveries guided by AI, specifically, we can expand the toolbox available for gene editing, which is crucial for therapeutic, diagnostic, and research applications… but also a great way to better understand the vast diversity of microbial defense mechanisms, said Feng Zhang, another CRISPR pioneer, molecular biologist, and core member at the Broad Institute of MIT and Harvard in an emailed statement to Fast Company.

ICYMI: In a groundbreaking achievement, researchers have successfully created a chimeric monkey with two different sets of DNA through the injection of stem cells from one monkey embryo into another of the same species.

[Source]

Scientists based in China have successfully created a chimeric monkey.

Continue reading “China creates world’s first chimeric monkey with fluorescent eyes, fingertips” »

With a demand for food and beverage (F&B) packaging inspection systems, the industry faces challenges. See how LandingLens & artificial intelligence can help.

In this episode, I am joined by Dr. David Sinclair, tenured Professor of Genetics at Harvard Medical School and an expert researcher in the field of longevity. Dr. Sinclair is also the author of the book Lifespan: Why We Age & Why We Don’t Have To, and the host of the Lifespan Podcast, which launches January 5, 2022. In this interview, we discuss the cellular and molecular mechanisms of aging and what we all can do to slow or reverse the aging process. We discuss fasting and supplementation with resveratrol, NAD, metformin, and NMN. We also discuss the use of caffeine, exercise, cold exposure, and why excessive iron load is bad for us. We discuss food choices for offsetting aging and promoting autophagy (clearance of dead cells). And we discuss the key blood markers everyone should monitor to determine your biological versus chronological age. We also discuss the future of longevity research and technology. This episode includes lots of basic science and specific, actionable protocols, right down to the details of what to do and when. By the end, you will have in-depth knowledge of the biology of aging and how to offset it. #HubermanLab #DavidSinclair #Longevity

A robot that automates a common technique for animal cloning has been used to produce a litter of cloned pigs in China — with a much higher success rate than human scientists.

The challenge: China is both the world’s biggest producer of pork and its largest consumer, so having ideal breeding stock — animals that birthe large litters of quick-growing piglets — is important for the nation’s economy and food security.

However, in 2018 and 2019, an epidemic of deadly African swine fever wiped out almost 50% of China’s pig population. As a result, many farmers have had to import breeding pigs, and China is now eager for its pork industry to become almost entirely self-sufficient.