Lifeboat Foundation

A who’s-who from the world of synthetic biological research have come together to launch Senti Biosciences with $53 million in funding from a slew of venture capital investors.

Led by Tim Lu, a longtime researcher at the Massachusetts Institute of Technology and one of the founding fathers of synthetic biology, Senti’s aim is nothing less than developing therapies that are tailored to an individual’s unique biology — and their first target is cancer.

Here’s how Lu described a potential cancer treatment using Senti’s technology to me. “We take a cell derived from humans that we can insert our genetic circuits into… we insert the DNA and encoding and deliver those cells via an IV infusion. We have engineered the cells to locate where the tumors are… What we’ve been doing is engineering those cells to selectively trigger an immune response against the tumor.”

Continue reading “All-star team of synthetic biologists raise $53 million for cancer therapy startup Senti” »

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Longevity become hottest object for investments;

Startup founded 5 moths ago just raised $250 million.

The start-up, which launched in September and is headquartered in Warren, N.J., announced Thursday it has raised $250 million in venture capital from global biopharmaceutical company Celgene, biotechnology company United Therapeutics Corporation, biopharmaceutical company Sorrento Therapeutics, DNA sequencing and machine learning company Human Longevity, Inc.

Continue reading “Will 100 be the new 60? Stem cell start-up that raised $250 million could extend lifespan” »

“Lloyds Banking Group Plc said on Sunday it would ban its credit card customers from buying Bitcoin and other cryptocurrencies.”

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“Greater ambition to divest from fossil fuel investments and consistent climate action is needed from the global investor community to accelerate the move towards a low-carbon economy and a climate-resilient future, top UN officials said at a major investor summit in New York this week.”

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Security experts say more of these hands-on demonstrations are needed to get an industry traditionally focused on physical protection to think more creatively about growing cyber threats. The extent to which their advice is heeded will determine how prepared nuclear facilities are for the next attack.

“Unless we start to think more creatively, more inclusively, and have cross-functional thinking going into this, we’re going to stay with a very old-fashioned [security] model which I think is potentially vulnerable,” said Roger Howsley, executive director of the World Institute for Nuclear Security (WINS).

The stakes are high for this multibillion-dollar sector: a cyberattack combined with a physical one could, in theory, lead to the release of radiation or the theft of fissile material. However remote the possibility, the nuclear industry doesn’t have the luxury of banking on probabilities. And even a minor attack on a plant’s IT systems could further erode public confidence in nuclear power. It is this cruelly small room for error that motivates some in the industry to imagine what, until fairly recently, was unimaginable.

Continue reading “Behind the simulations imagining the nuclear apocalypse” »

A new analysis of global science and engineering competence shows that the United States is struggling to fight off an increasingly competitive China.

The numbers: According to the National Science Foundation, China published over 426,000 research papers in 2016. America pumped out almost 409,000. If you consider the number of citations for those papers, a measure of the influence they have in the scientific community, America does better—it placed third internationally, while China comes in fifth (Sweden and Switzerland took the top spots).

Strengths elsewhere: The report does, however, note that America invests the most in R&D, attracts the most venture capital, and awards the most advanced degrees compared with every other nation in the world.

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Standard utopias and standard dystopias are each perfect after their own particular fashion. We live somewhere queasier—a world in which technology is developing in ways that make it increasingly hard to distinguish human beings from artificial things. The world that the Internet and social media have created is less a system than an ecology, a proliferation of unexpected niches, and entities created and adapted to exploit them in deceptive ways. Vast commercial architectures are being colonized by quasi-autonomous parasites. Scammers have built algorithms to write fake books from scratch to sell on Amazon, compiling and modifying text from other books and online sources such as Wikipedia, to fool buyers or to take advantage of loopholes in Amazon’s compensation structure. Much of the world’s financial system is made out of bots—automated systems designed to continually probe markets for fleeting arbitrage opportunities. Less sophisticated programs plague online commerce systems such as eBay and Amazon, occasionally with extraordinary consequences, as when two warring bots bid the price of a biology book up to $23,698,655.93 (plus $3.99 shipping).

In other words, we live in Philip K. Dick’s future, not George Orwell’s or Aldous Huxley’s. Dick was no better a prophet of technology than any science fiction writer, and was arguably worse than most. His imagined worlds jam together odd bits of fifties’ and sixties’ California with rocket ships, drugs, and social speculation. Dick usually wrote in a hurry and for money, and sometimes under the influence of drugs or a recent and urgent personal religious revelation.

Still, what he captured with genius was the ontological unease of a world in which the human and the abhuman, the real and the fake, blur together. As Dick described his work (in the opening essay to his 1985 collection, I Hope I Shall Arrive Soon):

Continue reading “Philip K. Dick and the Fake Humans” »

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