Lifeboat Foundation

In the intensive care unit (ICU), critically ill patients are cared for by a multidisciplinary care team. Compassionate and caring behaviors on the part of the care team result in better outcomes for patients and their families, and care providers entering the demanding field of medicine because they wish to help people and relieve suffering. However, studies have demonstrated deficiencies in delivering compassionate health care. Evidence suggests that physicians may miss up to 90% of opportunities to respond to patients with compassion.

To determine what factors drive and enhance compassionate care behaviors in the ICU setting and which factors drain and negate caring attitudes and behaviors, Shahla Siddiqui, MD, MSc, FCCM, and a colleague conducted an observational, qualitative study of an international panel of intensive and critical care providers. The researcher-clinicians report in PLOS ONE that while ICU physicians and nurses feel a deep moral imperative to deliver the highest level of compassionate care, pressures of capacity strain, lack of staff, lack of compassionate skills training and a heavy emphasis on electronic health record maintenance present significant hurdles to achieving that goal.

“Studies done on physician compassion from a patient perspective emphasize listening and awareness of the patient’s emotional state, which not only builds trust within the patient-physician relationship but also enhances resilience amongst the care team and prevents burnout,” said Siddiqui, an anesthesiologist at BIDMC. “Our aim was to describe compassionate behaviors in the ICU, study the factors that enhance and those that drain such behaviors with an aim to enable recommendations for practice and training.”

If all artists take inspiration from previous artists’ work, does AI art really pose a new threat to human creativity?

The journal Nature published a groundbreaking new study by world-renowned Stanford neuroscientist Sergiu Pasca involving the transfer of human brain organoids into the brains of rats. Insoo Hyun, Director of the Center for Life Sciences and Public Learning at the Museum of Science, speaks candidly with Dr. Pasca about his research. Why did he do it? How might this uncover the mysteries of psychiatric disorders? And the Big Question we are all wondering about – can these rats ever develop “human-like” consciousness? Together they demystify the science.

00:33 Dr. Sergiu Pasca’s Romanian roots.
00:55 Why is Dr. Pasca’s work important for Psychiatry?
04:14 Dr. Pasca’s work with human brain organoids.
06:14 Challenges with using animal brains when trying to unlock mysteries of human psychiatric disorders.
07:13 Reason for Dr. Pasca’s latest research transplanting human brain organoids into rat brains.
08:47 How the human brain organoid transplantation into a rat brain is accomplished.
10:19 What Dr. Pasca learned from his experiment and its importance.
12:02 Brain cells’ amazing ability to take over and organize themselves in appropriate environments.
13:03 Will animals with human brain organoids in their brain develop human-like consciousness?
17:30 Will manipulating human neurons in a rat change the behavior of the rat?
19:43 Application of rat experiment findings for human patients.
22:07 The ethics and regulation of using animals in scientific research.
25:25 Why context matters in research of transplanting human brain organoids into rat brains and the challenge of people backfilling science they might not understand with mythology and science fiction.
32:28 Dr. Pasca’s inspiration to work so hard to unlock the mysteries of psychiatric disorders.

Continue reading “Using Human Brain Cells in Rats to Understand Psychiatric Disorders with Dr. Sergiu Pasca” »

If a free-floating brain could feel pain or ‘wake up,’ how would we know? That’s an important ethical question — and it’s one we need to ask more often as labs around the world create new organoids, or miniature human organs. To answer it we talked to Jay Gopalakrishnan at his ‘mini brain’ lab for centrosome and cytoskeleton biology in Düsseldorf, Germany.

STUDY: https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(21)00295-2

Continue reading “Inside a mini-brain (with eyes?) lab” »

Derk Pereboom claims that free will is impossible because of its incompatibility with both determinism and indeterminism. Also he defends a robust nonreductive physicalism. It says that although consciousness can’t be reduced to physical it’s not something over and above physical.
The interview was taken by Vadim Vasiliev and Dmitry Volkov. Below you’ll see a list of questions of the interview.
1. The most influential books.
2. What are the differences between notions of moral responsibility and basic desert?
3. Which type of punishment should be eliminated if we find out that there is no justification for basic desert?
4. Is indignation as a reaction on wrongdoing a kind of irrational emotion?
5. How was the manipulation argument invented?
6. Why you’ve recently changed a presentation of the first case of Manipulation Argument?
7. How does the problem of free will relate to the problem of mental causation?
8. Could the problem of personal identity pose difficulties for moral responsibility and for basic desert? And why causal determinism is at the focus of free will debate?
9. Is there a real difference between hard incompatibilist’s position and that of compatibilists?
10. Can you list or name some differences and similarities between you and Daniel Dennett?
11. Could cognitive science and neuroscience eliminate the discussion on free will?
12. What is a definition of mental?
13. What were the most important changes of your views?
14. What is meaning of life?
15. What is your current research?

Brainoids — tiny clumps of human brain cells — are being turned into living artificial intelligence machines, capable of carrying out tasks like solving complex equations. The team finds out how these brain organoids compare to normal computer-based AIs, and they explore the ethics of it all.

Sickle cell disease is now curable, thanks to a pioneering trial with CRISPR gene editing. The team shares the story of a woman whose life has been transformed by the treatment.

We can now hear the sound of the afterglow of the big bang, the radiation in the universe known as the cosmic microwave background. The team shares the eerie piece that has been transposed for human ears, named by researchers The Echo of Eternity.

Microsoft’s latest layoffs throw ethics out the window and we should all be worried.

FallenKingdomReads’ list of The Top 5 Science Fiction Books That Explore the Ethics of Cloning.

Cloning is a topic that has been explored in science fiction for many years, often raising questions about the ethics of creating new life forms. While the idea of cloning has been discussed in various forms of media, such as movies and TV shows, some of the most interesting and thought-provoking discussions on the topic can be found in books. Here are the top 5 science fiction books that explore the ethics of cloning.

Alastair Reynolds’ House of Suns is a space opera that explores the ethics of cloning on a grand scale. The book follows the journey of a group of cloned human beings known as “shatterlings” who travel the galaxy and interact with various other sentient beings. The book raises questions about the nature of identity and the value of individuality, as the shatterlings face challenges that force them to confront their own existence and the choices they have made.

Microsoft laid off an entire team dedicated to guiding AI innovation that leads to ethical, responsible and sustainable outcomes. The cutting of the ethics and society team, as reported by Platformer, is part of a recent spate of layoffs that affected 10,000 employees across the company.

The elimination of the team comes as Microsoft invests billions more dollars into its partnership with OpenAI, the startup behind art-and text-generating AI systems like ChatGPT and DALL-E 2, and revamps its Bing search engine and Edge web browser to be powered by a new, next-generation large language model that is “more powerful than ChatGPT and customized specifically for search.”

The move calls into question Microsoft’s commitment to ensuring its product design and AI principles are closely intertwined at a time when the company is making its controversial AI tools available to the mainstream.