Lifeboat Foundation

Year 2021 Biocomputing is the future for the biological singularity because we could control all inputs and outputs of our bodies even evolve them eventually.

A silicon device that can change skin tissue into blood vessels and nerve cells has advanced from prototype to standardized fabrication, meaning it can now be made in a consistent, reproducible way. As reported in Nature Protocols, this work, developed by researchers at the Indiana University School of Medicine, takes the device one step closer to potential use as a treatment for people with a variety of health concerns.

The technology, called tissue nanotransfection, is a non-invasive nanochip device that can reprogram tissue function by applying a harmless electric spark to deliver specific genes in a fraction of a second. In laboratory studies, the device successfully converted skin tissue into blood vessels to repair a badly injured leg. The technology is currently being used to reprogram tissue for different kinds of therapies, such as repairing brain damage caused by stroke or preventing and reversing nerve damage caused by diabetes.

Continue reading “Innovative silicon nanochip can reprogram biological tissue in living body” »

Year 2023 Super tcells found in people that defeated cancer face_with_colon_three Basically tcells naturally eat cancer this therapy could lead to boosting the percentage of success rates in battling cancer.

Detailed characterization of the recognition and activation characteristics of T cells from successful therapy against melanoma unveils that individual T cells recognize multiple tumor-associated antigens simultaneously; elicitation or engineering of such “multipronged” T cells may be an effective means of enhancing the efficacy of T cell cancer therapy.

A team in Cornell Engineering created a new lithium battery that can charge in under five minutes – faster than any such battery on the market – while maintaining stable performance over extended cycles of charging and discharging.

The breakthrough could alleviate “range anxiety” among drivers who worry electric vehicles cannot travel long distances without a time-consuming recharge.

“Range anxiety is a greater barrier to electrification in transportation than any of the other barriers, like cost and capability of batteries, and we have identified a pathway to eliminate it using rational electrode designs,” said Lynden Archer, Cornell’s James A. Friend Family Distinguished Professor of Engineering and dean of Cornell Engineering, who oversaw the project. “If you can charge an EV battery in five minutes, I mean, gosh, you don’t need to have a battery that’s big enough for a 300-mile range. You can settle for less, which could reduce the cost of EVs, enabling wider adoption.”

For the past decade, researchers have been exploring hafnia’s ferroelectric properties, particularly in a crystal phase where it exhibits electric polarization.

To revolutionize high-performance computing, scientists and engineers are making strides in harnessing the potential of hafnium oxide, commonly known as hafnia. The latest study outlines processes for manipulating hafnia, aiming to pave the way for the next generation of computing memory.

For the past decade, researchers have explored hafnia’s ferroelectric properties, particularly in a crystal phase exhibiting electric polarization.

Continue reading “These hafnia molecules could pave the way for next-gen memory devices” »

Skoltech researchers and their colleagues from MIPT and China’s Center for High Pressure Science and Technology Advanced Research have computationally explored the stability of the bizarre compounds of hydrogen, lanthanum, and magnesium that exist at very high pressures. In addition to matching the various three-element combinations to the conditions at which they are stable, the team discovered five completely new compounds of hydrogen and either magnesium or lanthanum only.

Published in Materials Today Physics, the study is part of the ongoing search for room-temperature superconductors, the discovery of which would have enormous consequences for power engineering, transportation, computers and more.

“In the previously unexplored system of hydrogen, lanthanum, and magnesium, we find LaMg₃H₂₈ to be the ‘warmest’ superconductor. It loses electrical resistance below −109°C, at about 2 million atmospheres—not a record, but not bad at all either,” the study’s principal investigator, Professor Artem R. Oganov of Skoltech, commented.

Quantum engineering, a dynamic discipline bridging the fundamentals of quantum mechanics and established engineering fields has developed significantly in the past few decades. Two-level systems such as superconducting quantum bits are the building blocks of quantum circuits. Qubits of this type are currently the most researched and used in quantum computing applications^1,2,3,4,5. The characteristics of the superconducting qubits such as eigen energies, non-linearity, coupling strengths etc. can be tailored easily by adjusting the design parameters^6,7. Qubits have large non-linearity, which makes it possible to selectively address and control them^1,3,7,8. This dynamic property makes superconducting qubits a strong candidate for plethora of applications. Other two-level microscopic quantum systems^{9,10,11,12,13,14} also have certain advantages and may be used in the future.

Quantum devices operate at low temperatures and require good isolation from external noises. Microwave devices, such as circulators and isolators, protect quantum circuits by unidirectionally routing the output signal, whilst simultaneously isolating noise from the output channel back to the quantum circuit. Their non-reciprocal character relies on the properties of ferrites^15,16,17. Ferrite-based non-reciprocal devices are bulky^15,16,17, and they cannot be positioned near the quantum circuit because they require strong magnetic fields. Although commercial ferrite based non-reciprocal devices harness high isolation and low insertion loss, their dependency on magnetic components limits the scalability of cryogenic quantum circuits^15,16,18,19. Various ferrite-free approaches based on non-linear behavior of artificial atoms¹⁶, dc superconducting quantum interference devices (dc-SQUID)^20,21, and arrays of Josephson junctions (JJ’s)^19,22,23,24, have been experimentally demonstrated and implemented. Recently, a circuit based on semiconductor mixers has been used to realize a compact microwave isolator, which the authors claim could be extended to an on-chip device using Josephson mixers, although the “on-chip” demonstration is not yet reported²⁵. Additionally, mesoscopic circulators exploiting the quantum Hall effect to break time-reversal symmetry of electrical transport in 2D systems are explored at a cost of larger magnetic fields deleterious to superconducting circuits^{18,26,27,28,29}. More recently, a passive on-chip circulator based on three Josephson elements operating in charge-sensitive regime was demonstrated³⁰. Such devices are frequently limited by their parameter regime, leaving them charge sensitive and therefore difficult to implement in a practical scenario. However, it is possible to mitigate the charge-sensitivity by carefully tuning the device parameters. Our device operates in a parameter regime that is not sensitive to charge fluctuations or charge parity switching, a fundamental requirement for any practical implementation, and requires small magnetic field. The reported device is a proof of concept (PoC), potentially useful in the applications relevant to microwave read-out components in the field of superconducting quantum circuits.

In this work, we present a robust and simple on-chip microwave diode demonstrating transmission rectification based on a superconducting flux qubit⁸. The concept of the device is shown in Fig. 1a. The flux qubit is inductively coupled to two superconducting resonators of different lengths with different coupling strengths. The design details are reported later in this section. Probing the qubit at the half-flux (degeneracy point) with one tone-spectroscopy, we observe identical patterns of transmission coefficient for signals propagating in the opposite directions, which are shifted by 5 dB in power. This shift indicates the non-reciprocal behaviour in our device, expressed in terms of transmission rectification ratio ® in this article. The origin of this effect is the non-linearity of the flux qubit, which controls the transmission coefficient of the whole structure.

Researchers at the Georgia Institute of Technology have developed a light-based means of printing nano-sized metal structures that is significantly faster and cheaper than any technology currently available. It is a scalable solution that could transform a scientific field long reliant on technologies that are prohibitively expensive and slow. The breakthrough has the potential to bring new technologies out of labs and into the world.

Technological advances in many fields rely on the ability to print metallic structures that are nano-sized—a scale hundreds of times smaller than the width of a human hair. Sourabh Saha, assistant professor in the George W. Woodruff School of Mechanical Engineering, and Jungho Choi, a Ph.D. student in Saha’s lab, developed a technique for printing metal nanostructures that is 480 times faster and 35 times cheaper than the current conventional method.

Their research is published in the journal Advanced Materials.

Researchers from the School of Biomedical Engineering & Imaging Sciences have published a new study exploring the use of positron emission particle tracking (PEPT) in a living subject for the first time.

PEPT technology allows for the 3D localization and tracking of a single radioactive particle within large, dense, and/or optically opaque systems, which is difficult to study using other methodologies. The technology is currently used to study flows within complex mechanical systems such as large engines, industrial mixers, etc., but has not yet been translated for use in biomedical applications.

PEPT has previously been an unexplored area in biomedical imaging due to the lack of methods to isolate and radiolabel a single particle of a small enough size and with enough radioactivity which to would enable it to be injected and detected in a living subject.

The possibility of direct interfacing between biological and technological information devices could result in a merger of mind and machine — Ultimate Computing. This book, a thorough consideration of this idea, involves a number of disciplines, including biochemistry, cognitive science, computer science, engineering, mathematics, microbiology, molecular biology, pharmacology, philosophy, physics, physiology, and psychology.