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Archive for the ‘chemistry’ category: Page 281

Jun 18, 2020

Biochemical Quantitative Phase Imaging Delivers Unprecedented 3D Images of Live Cells Plus Details of Molecules Inside

Posted by in categories: biotech/medical, chemistry

No damage caused by strong light, no artificial dyes or fluorescent tags needed.

The insides of living cells can be seen in their natural state in greater detail than ever before using a new technique developed by researchers in Japan. This advance should help reveal the complex and fragile biological interactions of medical mysteries, like how stem cells develop or how to deliver drugs more effectively.

“Our system is based on a simple concept, which is one of its advantages,” said Associate Professor Takuro Ideguchi from the University of Tokyo Research Institute for Photon Science and Technology. The results of Ideguchi’s team were published recently in Optica, the Optical Society’s research journal.

Jun 17, 2020

Lithium-ion batteries take chemistry Nobel

Posted by in categories: chemistry, electronics

Chemistry Nobel

Olof Ramström, from the Nobel Committee, said lithium-ion batteries had “enabled the mobile world”.


Three scientists have been awarded the 2019 Nobel Prize in Chemistry for the development of lithium-ion batteries.

Continue reading “Lithium-ion batteries take chemistry Nobel” »

Jun 16, 2020

MIT Makes Tissue – Such as Human Brain – Stretchable, Compressible, and Nearly Indestructible

Posted by in categories: bioengineering, biotech/medical, chemistry, genetics, neuroscience

Chemical process called ELAST allows labeling probes to infuse more quickly, and makes samples tough enough for repeated handling.

When there’s a vexing problem to be solved, people sometimes offer metaphorical advice such as “stretching the mind” or engaging in “flexible” thinking, but in confronting a problem facing many biomedical research labs, a team of MIT researchers has engineered a solution that is much more literal. To make imaging cells and molecules in brain and other large tissues easier while also making samples tough enough for years of handling in the lab, they have come up with a chemical process that makes tissue stretchable, compressible, and pretty much indestructible.

“ELAST” technology, described in a new paper in Nature Methods, provides scientists a very fast way to fluorescently label cells, proteins, genetic material, and other molecules within brains, kidneys, lungs, hearts, and other organs. That’s because when such tissues can be stretched out or squished down thin, labeling probes can infuse them far more rapidly. Several demonstrations in the paper show that even after repeated expansions or compressions to speed up labeling, tissues snap back to their original form unaltered except for the new labels.

Jun 16, 2020

Artificial Synapse That Works With Living Cells Developed at Stanford

Posted by in categories: chemistry, energy

In 2017, Stanford University researchers presented a new device that mimics the brain’s efficient and low-energy neural learning process. It was an artificial version of a synapse — the gap across which neurotransmitters travel to communicate between neurons — made from organic materials. In 2019, the researchers assembled nine of their artificial synapses together in an array, showing that they could be simultaneously programmed to mimic the parallel operation of the brain.

Now, in a paper published June 15 in Nature Materials, they have tested the first biohybrid version of their artificial synapse and demonstrated that it can communicate with living cells. Future technologies stemming from this device could function by responding directly to chemical signals from the brain. The research was conducted in collaboration with researchers at Istituto Italiano di Tecnologia (Italian Institute of Technology – IIT) in Italy and at Eindhoven University of Technology (Netherlands).

“This paper really highlights the unique strength of the materials that we use in being able to interact with living matter,” said Alberto Salleo, professor of materials science and engineering at Stanford and co-senior author of the paper. “The cells are happy sitting on the soft polymer. But the compatibility goes deeper: These materials work with the same molecules neurons use naturally.”

Jun 15, 2020

Human Eggs Can Choose the Sperm They Prefer

Posted by in category: chemistry

While people usually put a lot of effort into finding a partner, recent research suggests that our bodies are choosy in their own ways. Chemical signals that are released by human eggs can attract sperm, and new work has shown that eggs also use these molecules to ‘select’ the sperm they want. The findings, reported in Proceedings of the Royal Society B, showed that eggs also don’t always pick the same sperm; eggs from different women can opt for sperm from different men.

Continue reading “Human Eggs Can Choose the Sperm They Prefer” »

Jun 14, 2020

Exploring chemical compound space with quantum-based machine learning

Posted by in categories: chemistry, quantum physics, robotics/AI, space

Rational design of compounds with specific properties requires understanding and fast evaluation of molecular properties throughout chemical compound space — the huge set of all potentially stable molecules. Recent advances in combining quantum-mechanical calculations with machine learning provide powerful tools for exploring wide swathes of chemical compound space. We present our perspective on this exciting and quickly developing field by discussing key advances in the development and applications of quantum-mechanics-based machine-learning methods to diverse compounds and properties, and outlining the challenges ahead. We argue that significant progress in the exploration and understanding of chemical compound space can be made through a systematic combination of rigorous physical theories, comprehensive synthetic data sets of microscopic and macroscopic properties, and modern machine-learning methods that account for physical and chemical knowledge.

Jun 13, 2020

Solved: Fluid Mechanics Mystery That’s Been Puzzling Scientists for Decades

Posted by in categories: biotech/medical, chemistry

An Oregon State University environmental engineering professor has solved a decades-old mystery regarding the behavior of fluids, a field of study with widespread medical, industrial, and environmental applications.

The research by Brian D. Wood, published in the Journal of Fluid Mechanics, clears a roadblock that has been puzzling scientific minds for nearly 70 years and paves the way to a clearer picture of how chemicals mix in fluids.

A more complete grasp of that basic principle provides a foundation for advances in a range of areas – from how pollutants spread in the atmosphere to how drugs perfuse tissues within the human body.

Jun 13, 2020

From bacteria to you: The biological reactions that sustain our rhythms

Posted by in categories: biotech/medical, chemistry, evolution

Every second of every day, countless biochemical reactions take place in our bodies’ cells. The organization of this complex system is the result of billions of years of evolution, fine-tuning our functions since the first primordial organisms.

One such vital reaction is “methylation,” where a —a carbon atom linked to three hydrogen atoms—attaches itself to a target molecule. Methylation is involved in the regulation of everything from DNA to proteins, and it is so vital that it can be found in all .

In a recent paper published in Communications Biology, a team of researchers lead by Jean-Michel Fustin and Hitoshi Okamura from Kyoto University’s Graduate School of Pharmaceutical Sciences has uncovered an intimate connection between methylation and the body’s circadian rhythms: a link that exists even in organisms that don’t traditionally “sleep,” such as bacteria.

Jun 13, 2020

Breakthrough psilocybin study uncovers neurochemical origins of human ego

Posted by in categories: chemistry, neuroscience

“And by answering the question, how do psychedelics work, we also inadvertently shine a light on other questions science has shied away from for decades. How do our brains generate our sense of self? What is the neurochemistry of consciousness?”


New research asks, how does psilocybin create a feeling of ego dissolution, and what chemicals in the brain create our subjective sense of self?

Jun 12, 2020

Seismic waves reveal giant structures deep beneath Earth’s surface

Posted by in category: chemistry

Analysing data from hundreds of major earthquakes, Doyeon Kim at the University of Maryland and his colleagues have found a new structure beneath the volcanic Marquesas Islands in the South Pacific Ocean. The structure, known as an ultra-low velocity (ULV) zone, is about 1000 kilometres in diameter and 25 kilometres thick, says Kim.

These structures are called ULV zones because seismic waves pass through them at slower velocities, but what they are made of is still a mystery. They might be chemically distinct from Earth’s iron–nickel alloy core and silicate rock mantle, or have different thermal properties.

The researchers discovered the structure while analysing 7000 records of seismic activity from earthquakes that occurred around the Pacific Ocean basin between 1990 and 2018. The earthquakes all had a magnitude of 6.5 or greater, and were all deeper than 200 kilometres below Earth’s surface.