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This Water-Resistant Paper Could Revolutionize Packaging and Replace Plastic

A groundbreaking study showcases the creation of sustainable hydrophobic paper, enhanced by cellulose nanofibres and peptides, presenting a biodegradable alternative to petroleum-based materials, with potential uses in packaging and biomedical devices.

Researchers aimed to develop hydrophobic paper by leveraging the strength and water resistance of cellulose nanofibers, creating a sustainable, high-performance material suitable for packaging and biomedical applications. This innovative approach involved integrating short protein chains, known as peptide sequences, without chemically altering the cellulose nanofibers. The result is a potential alternative to petroleum-based materials, with significant environmental benefits.

The study, titled “Nanocellulose-short peptide self-assembly for improved mechanical strength and barrier performance,” was recently featured on the cover of the Journal of Materials Chemistry B. The research was conducted by the “Giulio Natta” Department of Chemistry, Materials, and Chemical Engineering at Politecnico di Milano, in collaboration with Aalto University, the VTT-Technical Research Centre of Finland, and the SCITEC Institute of the CNR.

Building blocks of life can form long before stars

Early Formation of Life’s Building Blocks

A groundbreaking study published in Nature Astronomy has revealed that amino acids, essential for life, can form in dark interstellar clouds long before stars and planets emerge. Glycine, the simplest amino acid, was shown to form on the surface of icy dust grains in cold, energy-deprived environments through a process called “dark chemistry.” These findings challenge the long-standing belief that UV radiation was required to create glycine, significantly expanding our understanding of how life’s precursors emerge in space.

Scientists Warn Against Creation of Mirror Life That May Cause an Extinction

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Hello and welcome! My name is Anton and in this video, we will talk about the potential dangers of mirror life.
Links:

https://theconversation.com/mirror-life-forms-may-sound-like…ent-246013
https://www.nature.com/articles/s41565-024-01627-z.
https://www.nature.com/articles/s41557-023-01411-x.
Previous videos:


https://youtu.be/0MRGJNKACYs.
https://youtu.be/L1wkR-92Rys.
#chirality #biology #mirrorlife.

0:00 Mirror life?
0:40 Chirality and handedness of molecules and why it’s important.
2:40 Recent advances in biochemistry.
3:45 New technical report warns science.
4:50 All life is handed.
6:00 What this could do in theory.
7:45 Conclusions and additional propositions.

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Timely TGFβ signalling inhibition induces notochord

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The work, published today in Nature, marks a significant step forward in our ability to study how the human body takes shape during early development.

The notochord, a rod-shaped tissue, is a crucial part of the scaffold of the developing body. It is a defining feature of all animals with backbones and plays a critical role in organising the tissue in the developing embryo.

Despite its importance, the complexity of the structure has meant it has been missing in previous lab-grown models of human trunk development.

In this research, the scientists first analysed chicken embryos to understand exactly how the notochord forms naturally. By comparing this with existing published information from mouse and monkey embryos, they established the timing and sequence of the molecular signals needed to create notochord tissue.

With this blueprint, they produced a precise sequence of chemical signals and used this to coax human stem cells into forming a notochord.

The stem cells formed a miniature ‘trunk-like’ structure, which spontaneously elongated to 1–2 millimetres in length. It contained developing neural tissue and bone stem cells, arranged in a pattern that mirrors development in human embryos. This suggested that the notochord was encouraging cells to become the right type of tissue at the right place at the right time.

Donald Cram, Nobel Laureate and UCLA Chemist, Dies at 82

Donald J. Cram, a Nobel Prize-winning chemist who taught andconducted research at UCLA for more than 50 years and is remembered bythousands of undergraduates for singing and playing guitar in class, died ofcancer June 17 at his home in Palm Desert. He was 82.

A renowned scientist who was as comfortable riding the waveswith friends in the San Onofre Surfing Club as he was in his lab at UCLAconstructing complex molecular models, Cram won the Nobel Prize in 1987 and theNational Medal of Science in 1993 for his work in host-guest chemistry, a fieldhe helped to create. In 1998, he wasranked among the 75 most important chemists of the past 75 years byChemical and Engineering News.

“DonaldCram stands alone in the incredible variety, beauty and depth of hisaccomplishments,” read the citation for Cram’s National Medal of Science. “His investigations have helped give thisscience its form and sophistication. Hetruly brought art to science by making his science an art.”

Bedbugs Are Stronger Than Ever and Scientists Just Found Out Why

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Ever since then, researchers have marveled at the bedbug’s resilience. No matter what kind of chemical insecticide we throw at it, they manage to survive. This is due in large part to its development of insecticide resistance. Recent research conducted by Hidemasa Bono at Hiroshima University found that a series of genetic mutations explain the bedbug’s resistance to insecticides.

To figure that out, Bono and his team took a peek at the genome of an insecticide-resistant bedbug. They then compared it to bedbug samples collected in 2010 from a hotel in Hiroshima, along with wild bedbugs dating back to the 1950s. They used a technique called long-read sequencing to create nearly free and nearly error-free genomic maps to compare the various bedbugs across time. This allowed them to see several different mutations across the three types of bedbugs.

They found that the bedbug that came from the hotel had 19,895 times more resistance to one of the most common types of insecticide, pyrethroids, than the nonresistant genome. All told, they identified 729 resistant specific mutations. Some of these mutations are related directly to DNA damage response, cell cycle regulation, and insulin metabolism.

Revolutionizing Brain Diagnostics with Light and AI

Summary: A new “molecular lantern” technique allows researchers to monitor molecular changes in the brain non-invasively using a thin light-emitting probe. This innovative tool utilizes Raman spectroscopy to detect chemical changes caused by tumors, injuries, or other pathologies without altering the brain beforehand.

Unlike prior methods requiring genetic modifications, this approach analyzes natural brain tissue with high precision, offering significant potential for diagnosing and studying brain diseases. Future developments aim to integrate artificial intelligence to enhance diagnostic accuracy and explore diverse biomedical applications.

Can Atoms Touch Each Other? Unveiling the Mysteries of Particle Interaction!

At first glance, it might seem obvious that atoms touch each other, especially when you consider the material world around us. From the objects we handle to the materials we utilize, everything indeed appears very solid. However, the question of whether atoms actually “touch” as we understand it on a human level is far more intricate than it might seem. In fact, the answer hinges on how we define “touch,” a concept that shifts significantly at the atomic scale.

At the human scale, “touch” generally refers to the meeting of well-defined surfaces. For instance, when you place a glass on a table, you might say the two objects are touching because their outer surfaces overlap. However, at the atomic scale, this notion of contact becomes much more ambiguous. An atom is neither a solid object nor an entity with a clear boundary. It consists of a central nucleus made up of protons and neutrons, surrounded by a cloud of constantly moving electrons. This unpredictable movement means the electron cloud does not create a fixed and defined surface.

To understand what contact means between atoms, one must look into the internal structure of these particles and the interactions occurring between their electrons. Each atom is made up of a central nucleus surrounded by an electron cloud, which isn’t located at a specific spot but occupies areas known as orbitals. These orbitals are regions of probability where it’s more or less likely to find an electron at any given time. Their shape and organization vary depending on the chemical element of the atom, giving each type of atom unique characteristics.

Chronic Stress-Induced NETs May Aid Cancer Metastasis

Decades of research have established that chronic stress—from money worries, job problems, family tensions, or other sources—causes chemical changes in the body. In a new study, researchers have identified biological changes induced by stress that may help explain how it could cause a tumor to spread, or metastasize.


To conduct the study, the researchers used two established methods for modeling stress in mice. One is designed to mimic exposure to constant, low-level, predictable stress. The other simulates intermittent, unpredictable, mild stress.

They used these methods to induce chronic stress in two different mouse models of breast cancer. In both models, when the mice were exposed to stress using either method, they had both larger mammary tumors and more lung metastases than mice not exposed to stress.

But a series of follow-up experiments strongly suggested that this increased tumor growth and metastasis wasn’t being driven by the effects of stress on cancer cells themselves.

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