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Wonder drugs that target ‘zombie cells’ could reverse the ageing process and prevent diseases

With its pudgy body, tired eyes and hair loss, the lower mouse could easily be the father of the sprightly and alert animal nestling alongside.

But they are actually the same age, the result of extraordinary trials of drugs which are slowing down or even reversing the ageing process.

Scientists now believe that ageing itself is responsible for many major conditions such as Alzheimer’s, Parkinson’s, arthritis, cancer, heart disease, and diabetes. And they think they have found a way to turn it off.

2019 Gairdner Awards: Winners hailed for discoveries on DNA replication and power of stem cells to fight cancer

It is fitting, then, that the groundbreaking research he’s done on mental health has, in a very real way, improved the lives of millions of people in the developing world.

Dr. Patel is the 2019 recipient of the prestigious John Dirks Canada Gairdner Global Health Award, which recognizes “his world-leading research in global mental health, providing greater knowledge on the burden and the determinants of mental disorders in low- and middle-income countries and pioneering approach for the treatment of mental health in low-resource settings.”

Dr. Patel, a professor of global health at Harvard University, said, modestly, that his greatest achievement is “having generated knowledge to change hearts and minds about the importance of mental health everywhere in the world.”

Anti-evolution drugs could keep gambling bacteria from developing antibiotic resistance

Bacteria are fast evolving resistance to antibiotics, which is fast-tracking us to a future where our best drugs no longer work and simple infections become life-threatening once again. While new antibiotics are in the works, the bugs will eventually develop resistances to those too, so a longer term strategy might be to prevent them from evolving in the first place. A new study has found that bacteria use clever gambles to adapt – and showed how we could rig the game in our favor.

Scientists Create an Artificial Cell That Makes Its Own Energy

Artificial cells created inside the lab have taken another major step forward, with scientists developing cells that are able to produce their own chemical energy and synthesise parts of their own construction.

That makes these artificial cells a lot more like real, biological cells – cells that can construct and organise their own building blocks naturally.

Not only could this help us understand how real cells work and come into being in the first place, it could also be vital for a host of other areas of research – such as ongoing efforts to produce artificial organs and other body tissue to fight back against disease.

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