Japanese researchers have successfully eliminated the extra chromosome responsible for Down syndrome using CRISPR gene editing.

Dr. Mohammed Enayat has access to all sorts of experimental antiaging treatments at his clinic, but a core part of his longevity routine is pretty cheap and accessible: supplements.
Enayat told Business Insider that his most recent “biological age” tests, taken 18 months ago, said he was 24, or 17 years younger than his chronological age of 41. There’s no consensus on how to define or measure biological age, but Enayat used GlycanAge and TruAge PACE, which measure inflammation and epigenetics, respectively.
The primary care doctor, who’s also the founder of London’s Hum2n longevity clinic, has been closely tracking his health for the past seven years, using wearable tech, including an Oura ring and a Whoop strap, plus regular blood, urine, and microbiome tests.
As neuro-ophthalmology educators, we have sought ways to improve the teaching of pupil-related disorder, focusing on incorporating their dynamic aspects and active learning. Our solution is an app for smartphone and tablet devices. The app, Pupil Wizard, provides a digital textbook featuring a dynamic presentation of the key pupillary abnormalities. It allows the users to interact with a digital patient and explore how each condition responds to direct and indirect light stimuli, near focus, and changes in ambient light (Fig. 1). Moreover, the users can test their knowledge in quiz mode, where random pupillary abnormalities must be correctly identified and multiple-choice questions about them answered.
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A new cancer treatment discovered by the University of California San Diego Sanford Stem Cell Institute (SSCI) and developed by Aspera Biomedicines will undergo testing in outer space this spring — this as researchers prepare to launch a clinical trial of the drug on Earth.
Rebecsinib, an investigational cancer drug slated to begin a Phase 1 clinical trial this year for patients with high-risk myelofibrosis or secondary acute myeloid leukemia, will be tested aboard the International Space Station (ISS) on four of the deadliest cancer types: ovarian cancer, metastatic breast cancer, acute myeloid leukemia and glioblastoma multiforme.
June 12, 2025
Rebecsinib, a new cancer treatment discovered by UC San Diego Sanford Stem Cell Institute will undergo testing in outer space on an additional four of the deadliest cancer types: ovarian cancer, metastatic breast cancer, acute myeloid leukemia and glioblastoma multiforme.
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SENS Research Foundation works to develop, promote, and ensure widespread access to therapies that cure and prevent the diseases and disabilities of aging by comprehensively repairing the damage that builds up in our bodies over time.
A new study from The University of Texas at Arlington details a novel strategy for how the body clears out dead cells during stress, revealing unexpected roles for well-known stress-response genes—a discovery that could help scientists better understand diseases affecting the immune system, brain and metabolism.
“The body is constantly creating new cells and removing old cells once they die,” said Aladin Elkhalil, lead author of the study and a third-year doctoral student in the lab of Piya Ghose, assistant professor of biology at UT Arlington. “This removal of dead cells is just as important as creating new ones, because if the body is unable to rid itself of dead cells, it can lead to various health problems”
Published in PLOS Genetics, the study was conducted on the roundworm C. elegans by Dr. Ghose, Elkhalil and Alec Whited, another graduate student in the Ghose lab. This tiny, transparent organism is a widely used tool in genetic research because its see-through body allows scientists to observe live cell behavior, including how cells die. The research team took advantage of these unique features in several innovative ways.
The Hong Kong University of Science and Technology (HKUST)-led research team has adopted gyromagnetic double-zero-index metamaterials (GDZIMs) — a new optical extreme-parameter material – and developed a groundbreaking method to control light using GDZIMs. This discovery could revolutionize fields like optical communications, biomedical imaging, and nanotechnology, enabling advances in integrated photonic chips, high-fidelity optical communication, and quantum light sources.
Published in Nature, the study was co-led by Prof. CHAN Che-Ting, Interim Director of the HKUST Jockey Club Institute for Advanced Study and Chair Professor in the Department of Physics, and Dr. ZHANG Ruoyang, Visiting Scholar in the Department of Physics at HKUST.