Lifeboat Foundation

As leaders of calorie restriction research and practice, Meredith Averill and I often participate in media events. A recent news conference covered rapidly evolving aspects of calorie restriction research that anyone could benefit from, whether they choose to follow a low-calorie lifestyle or not. Therefore, we thought it appropriate to share the details of the event with the Lifeboat Foundation audience.

The conference was hosted by the American Federation of Aging Research (AFAR). AFAR is a forward-looking organization that provides financial support for early- and mid-career scientists who are developing careers in the study of aging.

This conference, entitled “You are What you Don’t Eat!” presented two world-famous CR scientists, Drs. Luigi Fontana and Donald Ingram. After an introduction from AFAR’s board member, Dr. Jack Watters, both scientists shared many profound insights that could extend healthy lifespan for millions of people.

Dr. Fontana first reminded us how important calorie restriction research is for the health and financial viability of the health care system: “Cardiovascular disease (CVD), cancer, stroke and diabetes account for nearly 70% of the deaths in the United States and Europe. About 80% of adults over 65 years of age have at least one chronic disease, and 50% have two or more of these chronic diseases that accelerate the aging process¹ .” The point he makes is that health care systems, especially with our rapidly aging population cannot sustain this large number of people with disease.

Continue reading “"You are What you Don't Eat!"” »

(NOTE: Selecting the “Switch to White” button on the upper right-hand corner of the screen may ease reading this text).

“Who are you?” A simple question sometimes requires a complex answer. When a Homeric hero is asked who he is.., his answer consists of more than just his name; he provides a list of his ancestors. The history of his family is an essential constituent of his identity. When the city of Aphrodisias… decided to honor a prominent citizen with a public funeral…, the decree in his honor identified him in the following manner:

Hermogenes, son of Hephaistion, the so-called Theodotos, one of the first and most illustrious citizens, a man who has as his ancestors men among the greatest and among those who built together the community and have lived in virtue, love of glory, many promises of benefactions, and the most beautiful deeds for the fatherland; a man who has been himself good and virtuous, a lover of the fatherland, a constructor, a benefactor of the polis, and a savior.
– Angelos Chaniotis, In Search of an Identity: European Discourses and Ancient Paradigms, 2010

I realize many may not have the time to read all of this post — let alone the treatise it introduces — so for those with just a few minutes to spare, consider abandoning the remainder of this introduction and spending a few moments with a brief narrative which distills the very essence of the problem at hand: On the Origin of Mass Extinctions: Darwin’s Nontrivial Error.

Continue reading “A (Relatively) Brief Introduction to The Principles of Economics & Evolution: A Survival Guide for the Inhabitants of Small Islands, Including the Inhabitants of the Small Island of Earth” »

Continue reading “The Existential Importance of Life Extension” »

It would be helpful to discuss these theoretical concepts because there could be significant practical and existential implications.

The Global Brain (GB) is an emergent world-wide entity of distributed intelligence, facilitated by communication and the meaningful interconnections between millions of humans via technology (such as the internet).

For my purposes I take it to mean the expressive integration of all (or the majority) of human brains through technology and communication, a Metasystem Transition from the human brain to a global (Earth) brain. The GB is truly global not only in geographical terms but also in function.

It has been suggested that the GB has clear analogies with the human brain. For example, the basic unit of the human brain (HB) is the neuron, whereas the basic unit of the GB is the human brain. Whilst the HB is space-restricted within our cranium, the GB is constrained within this planet. The HB contains several regions that have specific functions themselves, but are also connected to the whole (e.g. occipital cortex for vision, temporal cortex for auditory function, thalamus etc.). The GB contains several regions that have specific functions themselves, but are connected to the whole (e.g. search engines, governments, etc.).

Continue reading “The Global Brain and its role in Human Immortality” »

I believe that death due to ageing is not an absolute necessity of human nature. From the evolutionary point of view, we age because nature withholds energy for somatic (bodily) repairs and diverts it to the germ-cells (in order to assure the survival and evolution of the DNA). This is necessary so that the DNA is able to develop and achieve higher complexity.

Although this was a valid scenario until recently, we have now evolved to such a degree that we can use our intellect to achieve further cognitive complexity by manipulating our environment. This makes it unnecessary for the DNA to evolve along the path of natural selection (which is a slow and cumbersome, ‘hit-and-miss’ process), and allows us to develop quickly and more efficiently by using our brain as a means for achieving higher complexity. As a consequence, death through ageing becomes an illogical and unnecessary process. Humans must live much longer than the current lifespan of 80–120 years, in order for a more efficient global evolutionary development to take place.

It is possible to estimate how long the above process will take to mature (see figure below). Consider that the creation of the DNA was approximately 2 billion years ago, the formation of a neuron (cell) several million years ago, that of an effective brain (Homo sapiens sapiens) 200 000 years ago, and the establishment of complex societies (Ancient Greece, Rome, China etc.) thousands of years ago. There is a logarithmic reduction of the time necessary to proceed to the next more complex step (a reduction by a factor of 100). This means that global integration (and thus indefinite lifespans) will be achieved in a matter of decades (and certainly less than a century), starting from the 1960s-1970s (when globalisation in communications, travel and science/technology started to became established). This leaves another maximum of 50 years before the full global integration becomes established.

Each step is associated with a higher level of complexity, and takes a fraction of the timein order to mature, compared to the previous one.

Continue reading “Human Biological Immortality in 50 years” »

The Stoic philosophical school shares several ideas with modern attempts at prolonging human lifespan. The Stoics believed in a non-dualistic, deterministic paradigm, where logic and reason formed part of their everyday life. The aim was to attain virtue, taken to mean human excellence.

I have recently described a model specifically referring to indefinite lifespans, where human biological immortality is a necessary and inevitable consequence of natural evolution (for details see www.elpistheory.info and for a comprehensive summary see http://cid-3d83391d98a0f83a.office.live.com/browse.aspx/Immo…=155370157).

This model is based on a deterministic, non-dualistic approach, described by the laws of Chaos theory (dynamical systems) and suggests that, in order to accelerate the natural transition from human evolution by natural selection to a post-Darwinian domain (where indefinite lifespans are the norm) , it is necessary to lead a life of constant intellectual stimulation, innovation and avoidance of routine (see http://www.liebertonline.com/doi/abs/10.1089/rej.2005.8.96?journalCode=rej and http://www.liebertonline.com/doi/abs/10.1089/rej.2009.0996) i.e. to seek human virtue (excellence, brilliance, and wisdom, as opposed to mediocrity and routine). The search for intellectual excellence increases neural inputs which effect epigenetic changes that can up-regulate age repair mechanisms.

Thus it is possible to conciliate the Stoic ideas with the processes that lead to both technological and developmental Singularities, using approaches that are deeply embedded in human nature and transcend time.

(End of series. For previous topics please see parts I-IX)

Power plants. Trees could do a lot, as we have seen — and they’re solar powered, too. Once trees can suck metals from the soil and grow useful, shaped objects like copper wire, a few more levels of genetic engineering could enable the tree to use this copper wire to deliver electricity. Since a tree is already, now, a solar energy converter, we can build on that by having the tree grow tissues that convert energy into electricity. Electric eels can already do that, producing enough of a jolt to be lethal to humans. Even ordinary fish produce small amounts of electricity to create electric fields in the water around them. Any object nearby disrupts the field, enabling the fish to tell that something is near, even in total darkness. We may never be able to plug something into a swimming fish but we can already make batteries out of potatoes. So why not trees that grow into electricity providers all by themselves? It would be great to be able to plug your electrical devices into a tree (or at least a socket in your house that is connected to the tree). Then you would no longer need to connect to the grid, purchase solar panels, or install a windmill. You would, however, need to keep your trees healthy and vigorous! Tree care specialists would become a highly employable occupation.

Greening the desert. The Sahara and various other less notorious but still very dry deserts around the world have plenty of sand and rocks. But they don’t have much greenery. The main problem is lack of water. Vast swaths of the Sahara, for example, are plant free. It’s just too dry. However this problem is solvable! Cacti and other desert plants could potentially extract water from the air. Plants already extract carbon dioxide molecules from the air. Even very dry air contains considerable water vapor, so why not extract water molecules too. Indeed, plants already transport water molecules in the ground into their roots, so is it really such a big step to do the same from the air? Tillandsia (air plant) species can already pull in water with their leaves, but it has to be rain or other liquid water. Creating plants that can extract gaseous water vapor from the air in a harsh desert environment would require sophisticated genetic engineering, or a leap for mother nature, but it is still only the first step. Plants get nutrients out of the soil by absorbing fluid that has dissolved them, so dry soil would be a problem even for a plant that contained plenty of water pulled from the air. Another level of genetic engineering or natural evolution would be required to enable them to secrete fluid out of their roots to moisten chunks of soil to dissolve its minerals, and reabsorb the now nutritious, mineral-laden liquid back into their roots.

Once this difficult task is accomplished, whether by natural evolution in the distant future or genetic engineering sooner, things will be different in the desert. Canopies of vegetation that hide the ground will be possible. Thus shaded and sheltered, the ground will be able to support a much richer ecosystem of creatures and maybe even humans than is currently the case in deserts. One of Earth’s harshest environments would be tamed.

Continue reading “New Plant Paradigms (Part X: Power Plants, Greening the Desert, Phyto-Terraforming, and Recommendations)” »

Posted by Dr. Denise L Herzing and Dr. Lori Marino, Human-Nonhuman Relationship Board

Over the millennia humans and the rest of nature have coexisted in various relationships. However the intimate and interdependent nature of our relationship with other beings on the planet has been recently brought to light by the oil spill in the Gulf of Mexico. This ongoing environmental disaster is a prime example of “profit over principle” regarding non-human life. This spill threatens not only the reproductive viability of all flora and fauna in the affected ecosystems but also complex and sensitive non-human cultures like those we now recognize in dolphins and whales.

Although science has, for decades, documented the links and interdependence of ecosystems and species, the ethical dilemma now facing humans is at a critical level. For too long have we not recognized the true cost of our life styles and priorities of profit over the health of the planet and the nonhuman beings we share it with. If ever the time, this is a wake up call for humanity and a call to action. If humanity is to survive we need to make an urgent and long-term commitment to the health of the planet. The oceans, our food sources and the very oxygen we breathe may be dependent on our choices in the next 10 years.

And humanity’s survival is inextricably linked to that of the other beings we share this planet with. We need a new ethic.

Continue reading “The True Cost of Ignoring Nonhumans” »

The summer 2010 “Humanity+ @ Harvard — The Rise Of The Citizen Scientist” conference is being held, after the inaugural conference in Los Angeles in December 2009, on the East Coast, at Harvard University’s prestigious Science Hall on June 12–13. Futurist, inventor, and author of the NYT bestselling book “The Singularity Is Near”, Ray Kurzweil is going to be keynote speaker of the conference.

Also speaking at the H+ Summit @ Harvard is Aubrey de Grey, a biomedical gerontologist based in Cambridge, UK, and is the Chief Science Officer of SENS Foundation, a California-based charity dedicated to combating the aging process. His talk, “Hype and anti-hype in academic biogerontology research: a call to action”, will analyze the interplay of over-pessimistic and over-optimistic positions with regards of research and development of cures, and propose solutions to alleviate the negative effects of both.

Continue reading “Ray Kurzweil to keynote "H+ Summit @ Harvard — The Rise Of The Citizen Scientist"” »