Lifeboat Foundation

A team at Nottingham Trent University analyzed the full set of more than 11,000 gene transcripts inside muscle cells, finding that the ‘development pathways’—the different ways in which genes work together to regenerate muscle—become weakened in aged cells.

The study may help to shed some light on why muscle damage take longer to recover from as we age. The study is published in the Journal of Tissue Engineering and Regenerative Medicine.

The researchers developed a new approach to examine muscle cells in vitro in the laboratory to enable them to observe the different molecular mechanisms that drive muscle aging.

Water is a crucial and irreplaceable part of daily human life. As the world’s population expands and global temperatures rise, the demand for water proportionally increases.

In the last twenty years, worldwide water reserves have been depleting, even though the total storage capacity has expanded due to the building of additional reservoirs.

Led by Dr. Huilin Gao, associate professor in the Zachry Department of Civil and Environmental Engineering at Texas A&M University, researchers used a new approach with satellite data to estimate the storage variations of 7,245 global reservoirs from 1999 to 2018.

A makeshift lab in Fresno, California was illegally storing over 1,000 bioengineered mice and disease samples. Ana Kasparian and Wosney Lambre discuss on The Young Turks. https://shoptyt.com/collections/justice-is-coming.

Watch TYT LIVE on weekdays 6–8 pm ET. http://youtube.com/theyoungturks/live.

Continue reading “There Was A NASTY Illegal Lab Situation In California” »

Rotifers are excellent research organisms for studying the biology of aging, DNA repair mechanisms, and other fundamental questions. Now, using an innovative application of CRISPrCas9, scientists at the Marine Biological Laboratory, Woods Hole, have devised a method for making precise, heritable changes to the rotifer genome, enabling the larger community of scientists to deploy the rotifer as a genetically tractable lab organism.

An interdisciplinary team of mathematicians, engineers, physicists, and medical scientists has discovered a surprising connection between pure mathematics and genetics. This connection sheds light on the structure of neutral mutations and the evolution of organisms.

Number theory, the study of the properties of positive integers, is perhaps the purest form of mathematics. At first sight, it may seem far too abstract to apply to the natural world. In fact, the influential American number theorist Leonard Dickson wrote “Thank God that number theory is unsullied by any application.”

And yet, again and again, number theory finds unexpected applications in science and engineering, from leaf angles that (almost) universally follow the Fibonacci sequence, to modern encryption techniques based on factoring prime numbers. Now, researchers have demonstrated an unexpected link between number theory and evolutionary genetics.

Microorganisms leverage the CRISPR-Cas system as a defense mechanism against viral intrusions. In the realm of genetic engineering, this microbial immune system is repurposed for the targeted modification of the genetic makeup.

Under the leadership of Professor Dr. Alexander Probst, microbiologist at the Research Center One Health Ruhr at the Research Alliance Ruhr a research team has now discovered another function of this specialised genomic sequence: archaea – microorganisms that are often very similar to bacteria in appearance – also use them to fight parasites.

The team has recently published their findings in Nature Microbiology.

Biofilms are highly resistant communities of bacteria that pose a major challenge in the treatment of infections. While studying biofilm formation in laboratory conditions has been extensively conducted, understanding their development in the complex environment of the human respiratory tract has remained elusive.

A team of researchers led by Alexandre Persat at EPFL have now cracked the problem by successfully developing organoids called AirGels. Organoids are miniature, self-organized 3D tissues grown from stem cells to mimic actual body tissues and organs in the human body. They represent a paradigm shift in the field, enabling scientists to replicate and study the intricate environments of organs in the laboratory.

Developed by Tamara Rossy and her colleagues, the AirGels are bioengineered models of human lung tissue that open up new possibilities in infection research. They revolutionize infection research by accurately emulating the physiological properties of the airway mucosa, including mucus secretion and ciliary beating. This technology allows scientists to study airway infections in a more realistic and comprehensive manner, bridging the gap between in vitro studies and clinical observations.

This is older but this is just the tip of the iceberg. China is rumored to be working on genetic engineering to create “super soldiers” and they’re one country that isn’t stopped by ethics concerns. In the Prime TV series “The peripheral” it has something similar and I don’t want to spoil it beyond that. I think there’s a Vin Diesel movie called Blood Shot where he’s made into a super soldier. It’s a shame that this is used for warfare but the plus side is it’ll, some of the tech, will make its way down to civilian life such as the Internet did.

The plant hormone ethylene, in its gaseous state, has long been recognized for its ability to hasten fruit ripening and has a notable impact on shelf-life. In a recent study, scientists used the CRISPR/Cas9 system for gene editing to modify the ethylene production pathway in the luxury Japanese melon (Cucumis melo var. reticulatus “Harukei-3”) to increase its shelf-life.

Their findings were recently published in the journal Frontiers in Genome Editing.

The enzyme 1-aminocyclopropane-1-carboxylic acid.