One way to construct materials atom by atom is 
      to conscript machinery nature has already devised. 
      Scientists have methods of making round particles that are as small as 
      one nanometer, which is the span of 10 hydrogen atoms. But making more 
      complicated shapes is more difficult.
      Researchers from the University of Bristol in England, Vanderbilt 
      University, and the University of Maryland have found that they can fill 
      or coat a long, cylindrical tobacco virus with metal particles.
      The method could eventually be used to manufacture structures like 
      metal nanowires that could be used in electronics or optics devices, 
      according to the researchers.
      The researchers mixed the 4- by 60-nanometer virus with gold, silver 
      and platinum salts. In an acidic pH solution, negatively-charged metal 
      salts reacted with viral amino acids to cause nanoparticles to align on 
      the outer surface of the virus. In a neutral pH solution, 
      positively-charged salts passed through the viruses' protein coats, 
      causing metal nanoparticles to align inside the viruses.
      The researchers showed that mutating the amino acids affects where the 
      metal particles deposit.
      The method to be used practically in 10 to 20 years, according to the 
      researchers. The work appeared in the March 12, 2003 issue of Nano 
      Letters.